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001			81679
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007			cr nn 008mamaa
008			151105s2015 ne | s |||| 0|eng d
020			_a9789401774444
024	7		_a10.1007/978-94-017-7444-4 _2doi
050		4	_aRC584 _b.A454 2015
245	1	0	_aAllergy Bioinformatics _cedited by Ailin Tao, Eyal Raz.
250			_a1st ed. 2015.
260			_aDordrecht, Netherlands _bSpringer _c2015
300			_a1 recurso en línea (XII, 251 páginas) _b45 ilustraciones, 39 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aTranslational Bioinformatics _x2213-2775 _v8
505	0		_aAllergic Disease Epidemiology -- The Pathogenesis of Allergy: A Brief Introduction -- Genetics and Epigenetic Regulation in Allergic Diseases -- Cross-Reactivity -- From Allergen Extracts to Allergen Genes and Allergen Molecules -- Allergen Gene Cloning -- High Throughput Screening of Allergy -- Surrogate Markers for Allergen-Specific Immunotherapy -- Immune Responses to Allergens in Atopic Disease: Considerations for Bioinformatics -- Antigenicity, Immunogenicity and Allergenicity -- Bioinformatic Classifiers for Allergen Sequence Discrimination -- Strategies for the Modification and Evaluation of Allergenicity -- Bioinformatics Methods to Predict Allergen Epitopes -- Allergen Database.
520	3		_aThe book introduces the bioinformatics resources and tools available for the study of allergenicity. Allergy symptoms affect more than 25% of the population in industrialized countries. At the same time, biotechnology is a rapidly developing field, which often involves the introduction of potentially allergenic novel proteins into drugs or foods. It is essential to avoid transferring a gene that encodes a major allergenic protein (from any source) into a drug/food crop that did not previously contain that protein. Accurately distinguishing candidate genes from allergens before transferring them into a drug or food would aid preventive efforts to curb the rising incidence of allergies. Several public databases have been created in response to increasing allergen data. The resources provided by these databases have paved the way for the creation of specialized bioinformatics tools that allow allergenicity to be predicted. The book is a useful resource for biologists and biomedical informatics scientists, as well as clinicians. Dr. Ailin Tao is the chief of Guangdong Province Key Laboratory of Allergy & Clinical Immunology, Principal Investigator of the State Key Laboratory of Respiratory Disease, the Second Affiliated Hospital of Guangzhou Medical University; Dr. Prof. Eyal Raz is a Professor of Medicine at University of California, San Diego, La Jolla, California, USA. They collaborate very well on allergy research and this book editing.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, asignarmaterias, EBSPRINGER,
650		7	_aBiología molecular _2embne _9139103
650	2	7	_aBiología molecular _2embne _9139103
700	1		_aTao, Ailin _eeditor literario _994243 _0Local
700	1		_aRaz, Eyal _eeditor literario _994244 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-017-7444-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b1290269x _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gne _h0
945			_aRC584 .A454 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11572310 _z06-04-17
999			_c81679 _d81679 _x1