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020 _a9789401773805
024 7 _a10.1007/978-94-017-7380-5
_2doi
050 4 _aRC269
_b.I584 2015
245 1 0 _aIntercellular Communication in Cancer
_cedited by Mustapha Kandouz.
250 _a1st ed. 2015.
260 _aDordrecht, Netherlands
_bSpringer
_c2015
300 _a1 recurso en línea (VIII, 366 páginas)
_b37 ilustraciones, 34 ilustraciones en color
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _aPreface -- Contributors.-Â{u2979}yond the channel: Role of connexins in regulating normal and cancerous processes in the mammary gland.-Â{u2802}Â{u2820} Connexins: Bridging the gap between the tumor microenvironment and cancer cell communication in brain tumors -- MicroRNA and Gap Junctions in Glioblastoma cells: Implications for cellular therapy.-Â{u4E6E}namic regulation of adherens junctions: implication in cell differentiation and tumor development -- Cadherin-based cell-cell adhesions: adhesion structure, signalling and computational modeling.-Â{u5B63}cadherin/catenin complex modulations in human oral cancer.-Â{u2802}Â{u2802}Â{u0535}mor-derived exosomes in metastasis signaling and implications.-Â{u2802}Â{u2802}Â{u0535}nneling Nanotubes: Intercellular conduits for direct cell-to-cell communication in cancer.-Â{u396C}ll-Cell Fusion, Chemotaxis and Metastasis.-Â{u2BEC}e of the family of Ephs and Ephrins in non-junctional cell-cell communication in cancer.-Â{u3BED}mputational approaches to modeling of molecular interactions in multicellular systems.-Â{u3BEE}ntact Normalization or Escape from the Matrix.-Â{u9BB4}tercellular communication, the tumor microenvironment, and tumor progression.-Â{u9BA4}dex.
520 3 _aCells are by nature compelled to live in groups. They develop dependence over signaling cues received from their microenvironment, in particular from other cells, whether of their own “kindâ€{u0BF2} of a different type. Therefore, communicating with these cells is a critical aspect of their behavior and fate, as they live and die normally or as they undergo disease-related pathological changes, with dramatic repercussions. InÂ{u4A29}s book,Â{u7960}have asked expert researchers in the field of Intercellular Communication in Cancer to provide chapters on different aspects of interaction between neighboring cells, in the context of cancer diseases.Â{u7960}have specifically focused our efforts on membrane-to-membrane contact-based rather than growth factors-mediated modes of intercellular communications. The contributing authors provide an extensive overview of their respective area of specialization, with an in-depth discussion of the molecular mechanisms of cell-cell interactions, the impact on tumor progression and response to therapies, as well as the cancer diagnostic value of this scientific information. This bookÂ{u1A6D}s to introduce essential aspects of the normal and pathological cellular fate and homeostasis to both scientists and clinicians, and also to provide established researchers with an update on the novelties and future directions this expanding field is witnessing.
710 2 _aSpringerLink (Online service)
_0Local
_9106996
942 _2lcc
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988 _aEBOOK, asignarmaterias, EBSPRINGER,
650 7 _aInteracción celular
_2embne
_9667661
650 7 _aCélulas cancerosas
_2fast
_9146156
700 1 _aKandouz, Mustapha
_eeditor literario
_994232
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-017-7380-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b12902639
_b10-10-17
_c18-01-16
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