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007			cr nn 008mamaa
008			151005s2015 ne | s |||| 0|eng d
020			_a9789401772006
024	7		_a10.1007/978-94-017-7200-6 _2doi
050		4	_aRM301.27 _bT444 2015
245	1	4	_aThe Essential Guide to N-of-1 Trials in Health _cedited by Jane Nikles, Geoffrey Mitchell.
250			_a1st ed. 2015.
260			_aDordrecht, Netherlands _bSpringer _c2015
300			_a1 recurso en línea (XI, 245 páginas) _b31 ilustraciones, 17 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aPreface -- Introduction -- What are N-of-1 trials?- N-of-1 trials in the behavioural sciences -- N-of-1 trials in medical contexts -- Aggregated N-of-1 trials -- Methodological considerations for N-of-1 trials -- Randomization, allocation concealment and blinding -- Data collection and quality control -- Individual reporting of N-of-1 trials to patients and clinicians -- Assessing and reporting adverse events -- Research ethics and N-of-1 trials -- Statistical analysis of N-of-1 trials -- The economics of N-of-1 trials -- Reporting N-of-1 trials to professional audiences -- Single patient open trials -- Systematic review and meta-analysis using N-of-1 trials -- Where are N-of-1 trials headed?- Index.
520	3		_aN-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs. Â{u4A25}y have the potential to revolutionize the way clinical medicine is practiced. Whether you are a busy clinician, a researcher or a student, this book provides everything you need to know about N-of-1 trials. Written and edited by some of the worldâ€{u382C}eading experts on N-of-1 trials, the book presents state of the art knowledge about N-of-1 trials, with chapters on ethics, statistics, health economics, design, analysis and reporting, and more.Â{u6D6C}ll of examples and well illustrated, it is a comprehensive compendium of issues surrounding the design, conduct, interpretation and implementation of N-of-1 trials in a health system.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		7	_aFarmacia _0 _2embne _9137891
650		7	_aFarmacoterapia _0 _2embne _9671142
650		7	_aEstadística _0 _2embne _9138934
700	1		_aNikles, Jane _eeditor literario _994211 _0Local
700	1		_aMitchell, Geoffrey _eeditor literario _994212 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-94-017-7200-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12902470 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gne _h4
945			_aRM301.27 T444 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11572097 _z06-04-17
999			_c81657 _d81657 _x1