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001			81618
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007			cr nn 008mamaa
008			151126s2015 ja | s |||| 0|eng d
020			_a9784431557630
024	7		_a10.1007/978-4-431-55763-0 _2doi
050		4	_aQP86 _b.A356 2015
245	1	0	_aAging Mechanisms : _bLongevity, Metabolism, and Brain Aging _cedited by Nozomu Mori, Inhee Mook-Jung.
250			_a1st ed. 2015.
260			_aTokyo _bSpringer _c2015
300			_a1 recurso en línea (XIV, 439 páginas) _b85 ilustraciones, 63 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aPreface -- Part I From Hypotheses to Mechanisms -- Part II Human Longevity: Centenarianism and Progeria -- Part III Stem Cells, Cultured Neurons, and Lower Animal Models -- Part IV Metabolism: Factors Affecting Tissue Aging -- Part V Aging Brain: Adult Neurogenesis, Synaptic Plasticity, and Brain Volume -- Part VI Aged Brain: Mechanisms of Neurodegeneration -- Part VII Anti-Brain Aging: Neuroprotection and Therapeutic Approaches -- Epilogue -- Appendix -- Index. Â{uE000}
520	3		_aThis book brings together the most up-to-date information on recent research results of leading laboratories on aging science in East Asia, particularly in Japan, Korea, and Hong Kong. Starting with a comprehensive overview of various hypotheses on biological mechanisms of aging by Dr. Sataro Goto, each chapter covers broad aspects of the most recent findings in aging-related topics: centenarian studies and genome analysis of progeria, metabolic biochemistry and neurobiology, longevity controls in yeast and nematodes, oxidative stress and calorie restriction, and neurodegeneration mechanisms in Alzheimerâ€{u3821}nd Huntingtonâ€{u3824}iseases, with further potential therapeutic approaches to these age-related neurodegenerative diseases. Also included, in part, is a summary and the outcomes of a scientific discussion forum called the Asian Aging Core for Longevity (AACL) that has been held annually alternating between Japan and Korea during the last decade. This book can serve as a useful resource for finding appropriate collaborators in the areas it covers. The target readership is made up of graduate students and researchers at universities, medical and/or life-science schools, and biomedical and pharmaceutical institutes. Why does aging exist? How do we age? How is each organismâ€{u382C}ifespan determined? These are fundamental questions in the field. We may be still far from achieving a complete view of aging mechanisms, but this book, Aging Mechanisms, offers an excellent opportunity to become familiar with the most updated progress in the biomedical research of aging in Japan and Korea, the two leading nations for human longevity.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		0	_9140743 _aGeriatría _0
650		7	_aFisiología humana _0 _2embne _9140024
650		7	_aNeurociencias _0 _2embne _9158907
700	1		_aMori, Nozomu _eeditor literario _994144 _0Local
700	1		_aMook-Jung, Inhee _eeditor literario _994145 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-4-431-55763-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12902081 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gja _h0
945			_aQP86 .A356 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11571706 _z06-04-17
999			_c81618 _d81618 _x1