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003			ES-MaUEC
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007			cr nn 008mamaa
008			150202s2015 ja | s |||| 0|eng d
020			_a9784431553816
024	7		_a10.1007/978-4-431-55381-6 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP702.G577 _b2015 EB
245	0	0	_aSugar Chains : _bDecoding the Functions of Glycans _cedited by Tadashi Suzuki, Kazuaki Ohtsubo, Naoyuki Taniguchi.
264		1	_aTokyo _bSpringer _c2015
300			_a1 recurso en línea (VIII, 288 p.) _b87 ilustraciones, 41 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_a1 N-Glycans and Quality Control of Proteins -- 2 Glycan-Mediated Protein Transport from the Endoplasmic Reticulum -- 3 Gangliosides and T-Cell Immunity -- 4 Gangliosides Regulate Tumor Properties: With Focus on the Suppression of Metastasis-Associated ppGalNAc-T13 with GM1 -- 5 Role of Glycans in Viral Infection -- 6 Discovery and Applications of a Novel Human Pluripotent Stem Cell-Specific Lectin Probe rBC2LCN -- 7 Glycan Structure and Neural Plasticity -- 8 The Involvement of Midkine, a Heparin-Binding Growth Factor, in Cancer Development -- 9 Tumor-Associated Glycans and Their Functional Roles in the Multistep Process of Human Cancer Progression -- 10 Mammalian Sialidase and Tumor Development -- 11 Roles of Glycans in Immune Evasion from NK Immunity -- 12 Glycomic Analysis of Cancer -- 13 Glyco-Predisposing Factor of Diabetes -- 14 Macrophages Govern Ganglioside GM3 Expression in Adipocytes to Regulate Adipogenesis and Insulin Signaling in Homeostatic and Pathogenic Conditions -- 15 O-Mannosyl Glycan and Muscular Dystrophy -- 16 Glycans and Chronic Obstructive Pulmonary Disease (COPD) -- 17 α1,6-Fucosyltransferase Knockout Mice and Schizophrenia-Like Phenotype.Â{u282E}.
520			_aThis book presents the latest breakthrough results in glycobiology regarding the roles of glycans in relation to quality control and transport of protein, the immune system, viral infection, stem cells, the neural system, and various diseases such as cancer, diabetes, chronic obstructive pulmonary disease, muscular dystrophy, and schizophrenia. Although glycoscience has long been regarded as a very specialized field with no simple analytical method, the recent explosive progress in research continues to provide limitless evidence that glycan chains are the key component in various biological phenomena. Cell surface glycans, for example, change with developmental stages or environmental conditions and thus represent a “faceâ€{u0BE6} the cell that is utilized for identification of iPS and ES cells and as biomarkers in diagnosis or detection of cancer. This book comprises 17 chapters, each of which poses outstanding “glyco-relatedâ€{u0C75}estions enabling non-specialists to have a clearer idea about what the future direction for further investigation of glycans in their own research fields will be. Also including basic information to understand the nature of glycans, this title serves as an excellent “textbookâ€{u09AF}r researchers in diverse research fields who are not familiar with, but nevertheless interested in, glycan chains or sugar chains.
988			_aEBOOK, EBSPRINGER
650		7	_aBioquímica _2embne _9138639
700	1		_aSuzuki, Tadashi _eeditor literario _994116 _0Local
700	1		_aOhtsubo, Kazuaki _eeditor literario _994117 _0Local
700	1		_aTaniguchi, Naoyuki _eeditor literario _985826 _0Local
710	2		_aSpringerLink (Online service) _0Local _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-4-431-55381-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b11/2020 _dz _eIG _feng _gja _h0