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008			141205s2015 ja | s |||| 0|eng d
020			_a9784431552000
024	7		_a10.1007/978-4-431-55200-0 _2doi
050		4	_aRC121.A5 _bA443 2015
245	1	0	_aAmebiasis : _bBiology and Pathogenesis of Entamoeba _cedited by Tomoyoshi Nozaki, Alok Bhattacharya.
260			_aTokyo _bSpringer _c2015
300			_a1 recurso en línea (IX, 581 páginas) _b100 ilustraciones, 52 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aPreface -- 1 Introduction -- 2 The continuously expanding universe of Entamoeba -- 3 The genomics of Entamoebae: insights and challenges -- 4 Multilocus sequence typing system (MLST): Genetic diversity and genetic components to virulence -- 5 The tRNA gene-linked STRs and other genetic typing methods -- 6 Genetic manipulation techniques -- 7 Surveying Entamoeba histolytica transcriptome using massively parallel cDNA sequencing -- 8 Ribosomal RNA Genes and their Regulation in Entamoeba histolytica -- 9 Small RNAs and regulation of gene expression in Entamoeba histolytica -- 10 The Biology of Retrotransposition in Entamoeba histolytica -- 11 Entamoeba histolytica: Bridging the gap between environmental stress and epigenetic regulation -- 12 Phagocytosis in Entamoeba histolytica -- 13 Signalling pathways in E. histolytica -- 14 Transmembrane Kinases and their role in E. histolytica pathogenesis -- 15 Cell surface molecules as virulence determinants in Entamoeba histolytica -- 16 Mechanism of cell division in Entamoeba histolytica -- 17 Molecular basis of the trafficking of cysteine proteases and other soluble lysosomal proteins in Entamoeba histolytica -- 18 Mitosomes in Entamoeba histolytica -- 19 Metabolomic analysis of Entamoeba biology -- 20 Glucose metabolism and its controlling mechanisms in Entamoeba histolytica -- 21 Structural Biology of Cysteine Biosynthetic Pathway Enzymes -- 22 Archetypical and specialized DNA replication proteins in Entamoeba histolytica -- 23 Pathology, pathogenesis and experimental amebiasis -- 24 Innate Host Defenses in the Gut -- 25 Cysteine peptidases in pathogenesis -- 26 Host immunity and tissue destruction during liver abscess formation -- 27 The Effect of E. histolytica on Muc2 Mucin and Intestinal Permeability -- 28 Human Genetic Susceptibility to Amebiasis -- 29 Immune Response in Human Amoebiasis: a protective response? -- 30 Metronidazole and the Redox Biochemistry of Entamoeba histolytica -- 31 Thioredoxin Reductase and its Role as a New Drug Target -- 32 Drug development: old drugs and new lead -- 33 HETEROCYCLIC LEAD COMPOUNDS AGAINST AMOEBIASIS.
520	3		_aThis book documents and presents new developments in the study of amebiasis, one of the neglected tropical diseases. Nearly 50 million people worldwide are infected with the pathogen Entamoeba histolytica, causing large-scale morbidity and mortality particularly in developing countries. This book will help clinicians for better diagnosis and management of the disease, researchers for initiating research projects on some of the poorly understood aspects of the disease and the pathogen, and students for updating their knowledge. The subjects covered range from genomics and molecular and cell biology to drug resistance and new drug development, highlighting major advances in recent years in our understanding due to rapid progress in genomic and other biomedical technologies, such as visualization of molecular processes. Most of the chapters provide recent information based on latest publications. A few chapters describe some of the critical methodological issues that will be helpful for students and researchers interested in getting into the field. The contributing authors include almost all the active researchers and clinicians from around the world. This book will be a useful primary material and a valuable source of information for anyone interested in understanding amebiasis, its diagnosis, and treatment. It will also be useful to those who are interested in learning about the biology of early branching eukaryotes and protist pathogens.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		0	_9139394 _aParasitología _0
650		0	_9138907 _aBacteriología _0
650		7	_aPatología _0 _2embne _9138489
700	1		_aNozaki, Tomoyoshi _eeditor literario _994103 _0Local
700	1		_aBhattacharya, Alok _eeditor literario _994104 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-4-431-55200-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b1290188x _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gja _h0
945			_aRC121.A5 A443 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11571500 _z06-04-17
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