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007			cr nn 008mamaa
008			141030s2015 ja | s |||| 0|eng d
020			_a9784431548416
024	7		_a10.1007/978-4-431-54841-6 _2doi
050		4	_aQP552.G59 _bG593 2015
245	1	0	_aGlycoscience: Biology and Medicine _cedited by Naoyuki Taniguchi, Tamao Endo, Gerald W. Hart, Peter H. Seeberger, Chi-Huey Wong.
260			_aTokyo _bSpringer _c2015
300			_a1 recurso en línea (333 ilustraciones, 233 ilustraciones en color eReference.
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aA. Analytical and Structural Approach - Technical Description for Analyzing Glycan Structures (Reviewed by Yoshiki Yamaguchi): Overview -- EMARS -- Development of glycan array -- Development of glycan array -- Development of glycan array -- Development of glycan array -- Automated programmable one-pot synthesis of glycans -- Lectin array -- Lectin-glycan interaction based on glycan array data -- Glycoform-specific protein staining by lectin and antibody -- Glycosaminoglycans analysis -- Mass analysis -- Mass analysis -- IGOT-lectin capture -- Membrane electrophoresis -- HPLC nucleotide-sugar analysis -- Capillary electrophoresis -- HPLC PA-sugar -- Congenital disorders of glycosylation, analytical aspect -- Quality control of pharmaceutical products and biosimilars -- NMR -- NMR -- STD-NMR -- Conformational analysis of glycans and glycoproteins -- Glycolipid LC-MS -- MALDI-MS -- MALDI-MS -- Sulfoglycolipids -- GAG array -- X-ray -- REMD simulation -- MD simulation and computational screening -- B. Glycoinformatics - New Approach for Informatics and Databases for Glycoscience (Reviewed by Kiyoko F. Aoki-Kinoshita): Informatics overview -- MIRAGE project -- RINGS -- JCGGDB -- UniCarb-DB -- CIRES -- GLYCOSCIENCES.de -- CSDB, Plant and Bacterial Carbohydrate Structure Database -- MonosaccharideDB -- Glycome DB -- GlycoEpitope -- Sugar Bind DB -- GLYCAM -- CAZy -- 3D Lectines -- C. Chemoenzymatic Synthesis of Glycans - Chemical and Enzymatic Methods of Glycan Synthesis (Reviewed by Yasuhiro Kajihara and Peter Seeberger): Overview -- Chemical synthesis of glycans -- Chemical synthesis of glycans -- Chemical synthesis of glycans -- Synthesis of homogeneous glycoproteins -- Synthesis of homogeneous glycoproteins -- Synthesis of homogeneous glycoproteins -- Synthesis of homogeneous glycoproteins -- Synthesis of homogeneous glycoproteins -- Glycopeptide/glycoprotein synthesis -- Gangliosides synthesis -- Specific Glycosylation -- Furanoside chemistry -- Glycoside synthesis -- Carbohydrate Library Synthesis -- Development of sugar array -- Development of sugar array -- Development of sugar array -- Automated synthesis -- Automation in glycan synthesis -- GPI chemical synthesis -- Oligosialic acid synthesis -- Synthesis of sulfated glycans -- Synthesis of sulfated glycans -- Synthetic antitumor vaccines -- Synthetic carbohydrate antigens for HIV Vaccine Design -- Chemical approach in biology and disease -- Glycoenzyme inhibitors -- Glycoenzyme inhibitors -- Glycoenzymes in glycan analysis and synthesis -- Endo-enzymes -- Oxazoline derivatives -- Large-scale enzymatic synthesis of glycans with cofactor regeneration -- Large-scale enzymatic synthesis of glycans -- Chemoenzymatic synthesis -- Chemoenzymatic synthesis of heparins -- Chemoenzymatic synthesis of glycoproteins -- Multivalent glycan synthesis -- Biosynthesis of A and B blood group -- Glycosyltransferase structures -- Structural biology of oligosaccharyltransferase (OST) -- Chemoenzymatic synthesis of oligosaccharides and cancer and bacterial vaccines -- Neoglycoprotein and oligosaccharide synthesis -- Chemoenzymatic synthesis of glycoconjugates -- Synthesis of O-glycosylated proteins -- D. Imaging of Glycans - New Techniques for Imaging Glycans (Reviewed by Yasuhiro Kajihara and Chi-Huey Wong): Molecular probes for glycosylation: overview Imaging by Click Chemistry -- Imaging by Click Chemistry -- Imaging by Click Chemistry -- Chemical tools to detect Helicobacter pylori -- Enzymatic imaging -- PET imaging -- Glycoprotein imaging -- E. Neuroglycobiology - The Role of Glycans in Neurobiology and Neuroscience (Reviewed by Kenji Kadomatsu): Neuroglycobiology overview -- Neurochemistry and developmental neurobiology -- Glycans in neurobiology -- Glycosaminoglycans (GAGs) -- GAGs -- Polysialic acid -- Polysialic acid -- Glycolipids sialidase -- HNK-1 -- Ganglioside -- Single molecule imaging -- Glycolipid -- Heparan sulfate proteoglycans (HSPG) -- HSPG -- N-glycans and glial cells.
520	3		_aThe aim of the book is to provide a succinct overview of the current status of glycoscience from both basic biological and medical points of view and to propose future directions, in order to facilitate further integrations of glycoscience with other fields in biological and medical studies. Glycans (carbohydrate oligomers) are the so-called “building blocksâ€{u0BE6} carbohydrates, nucleic acids, proteins and lipids and play major roles in many biological phenomena as well as in various pathophysiological processes. However, this area of glycoscience has been neglected from the research community because glycan structures are very complex and functionally diverse and as compared to proteins and nucleic acids simple tools for the amplification, sequencing and auto-synthesis of glycans are not available. Many scientists in other fields of research have now realized that glycosylation, i.e. the addition of glycans to a protein backbone, is the most abundant post translational modification reactions and is an important field of research and sometimes they require a glycobiology and/or glycochemistry approach to be used. It is still difficult, however, for non-expert researchers to use these techniques. This book provides numerous but simple overviews of current topics and protocols for the experiments. The book is aimed at university students and above, including non-experts in the field of glycoscience.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		7	_aCitología _2embne _9139477
650	2	7	_aBioquímica _2embne _9138639
650	2	7	_aCitología _2embne _9139477
700	1		_aTaniguchi, Naoyuki _eeditor literario _985826 _0Local
700	1		_aEndo, Tamao _eeditor literario _994088 _0Local
700	1		_aHart, Gerald W. _eeditor literario _0Local _994089
700	1		_aSeeberger, Peter H _eeditor literario _994090 _0Local
700	1		_aWong, Chi-Huey _eeditor literario _994091 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-4-431-54841-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12901830 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gja _h0
945			_aQP552.G59 G593 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11571457 _z06-04-17
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