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007			cr nn 008mamaa
008			150706s2015 au | s |||| 0|eng d
020			_a9783709112328
024	7		_a10.1007/978-3-7091-1232-8 _2doi
040			_aES-MaUEC _bspa
050		4	_aQH588.S83 _bS746 2015
245	1	0	_aStem Cell Aging : _bMechanisms, Consequences, Rejuvenation _cedited by Hartmut Geiger, Heinrich Jasper, Maria Carolina Florian.
260			_aVienna _bSpringer _c2015
300			_a1 recurso en línea (XI, 354 páginas) _b33 ilustraciones, 32 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aIntroduction -- Stem cells, aging and longevity (overview) -- General mechanisms of stem cell aging (overview) -- Mechanisms of Stem Cell Aging in Model Organisms -- Yeast: Chronological aging -- Divisional aging -- Primarily germline -- stem cell aging -- Drosophila: Male germ line -- Female germ line -- Somatic stem cells (stress and regulation of hematopoietic precursors, intestinal stem cell agingÂ{u1BA4} regulation). Zebrafish -- Mechanisms of Stem Cell Aging in Mammalian Tissues.-Hematopoietic (Mouse/Human) -- Skin (Mouse/Human) -- Intestine (Mouse/Human) -- Muscle (Mouse/Human) -- Neuronal Tissues (Mouse/Human) -- Diseases of Aging and Stem Cells -- Chronic Myeloid Leukemia and Aging of Hematopoietic Stem Cells (Mouse/Human) -- Wound Healing Repair and Aging of Skin Stem Cells (Mouse/Human) -- Stem Cell Rejuvenation Muscle -- Hematopoietic -- Neuronal.
520	3		_aAging of somatic stem cells reduces cell function and results in dysfunctional organs and tissues, making it an underlying cause of diseases associated with aging. It might even be the primary cause for age-associated attrition of tissue function in organs that heavily rely on stem cells for maintaining homeostasis, like the skin, blood and intestines. Understanding the molecular and cellular mechanisms involved is critical for developing approaches to attenuate stem cell aging and could pave the way for improved quality of life among the elderly. Written by highly prominent experts in the field, this book presents the current state of knowledge on these mechanisms. It offers insights into stem cell function, explains in detail the mechanisms of stem cell aging in model organisms as well as mammalian systems, and describes related diseases and approaches to attenuating stem cell aging or achieving rejuvenation. The book is intended for all scientists and clinicians working with stem cells, aging mechanisms or age-related diseases.
650		7	_aCélulas madre _2embne _9160528
650	2	7	_aCélulas madre _2embne _9160528
650		7	_aInmunología _2embne _9138330
700	1		_aGeiger, Hartmut _eeditor literario _994074 _0Local
700	1		_aJasper, Heinrich _eeditor literario _994075 _0Local
700	1		_aFlorian, Maria Carolina _eeditor literario _994076 _0Local
710	2		_aSpringerLink (Online service) _0Local _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-7091-1232-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12901684 _b10-10-17 _c18-01-16
942			_2lcc _cLE
945			_aQH588.S83 S746 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11571305 _z06-04-17
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gau _h0