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008			150325s2015 gw | s |||| 0|eng d
020			_a9783662463062
024	7		_a10.1007/978-3-662-46306-2 _2doi
050		4	_aQH445.2 _bG466 2015
245	1	0	_aGenome Mapping and Genomics in Human and Non-Human Primates _cedited by Ravindranath Duggirala, Laura Almasy, Sarah Williams-Blangero, Solomon F.D. Paul, Chittaranjan Kole.
260			_aBerlin, Heidelberg _bSpringer _c2015
300			_a1 recurso en línea (VIII, 305 páginas) _b39 ilustraciones, 10 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aGenome Mapping and Genomics in Animals _v5
505	0		_aThe Utility of Genomics for Studying Primate Biology -- The Human Genome Project: Where Are We Now and Where Are We Going? -- Linkage Mapping: Localizing the Genes that Shape Human Variation -- Association Studies to Map Genes for Disease-Related Traits in Humans -- Gene Expression Studies and Complex Diseases -- Copy Number Variations and Chronic Diseases -- Applications of Genomic Methods to Studies of Wild Primate Populations -- Comparative Genomics: Tools for Study of Complex Diseases -- Genetic Structure and Its Implications for Genetic Epidemiology: Aleutian Island Populations -- Mapping Genes in Isolated Populations: Lessons from the Old Order Amish -- Genetics of Cardiovascular Disease in Minority Populations -- Mapping of Susceptibility Genes for Obesity, Type 2 Diabetes, and the Metabolic Syndrome in Human Populations -- Genetic Influence on the Human Brain -- Variation, Genetics, and Evolution of the Primate Craniofacial Complex -- Genetic Influences on Behavior in Nonhuman Primates -- Genomic Studies of Human Populations: Re-sequencing Approaches to the Identification of Human Quantitative Loci.
520	3		_aThis book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes including multifactorial diseases (e.g., cardiovascular disease, type 2 diabetes, and obesity), anatomic characteristics (e.g., the craniofacial complex), and neurological and behavioral phenotypes (e.g., human brain structure and nonhuman primate behavior) are presented. Topics covered include linkage and association methods, gene expression, copy number variation, next-generation sequencing, comparative genomics, population structure, and a discussion of the Human Genome Project. Further included are discussions of the use of statistical genetic and genetic epidemiologic techniques to decipher the genetic architecture of normal and disease-related complex phenotypes using data from both humans and non-human primates.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		0	_9162770 _aExpresión génica _0
650		7	_aEvolucionismo _0 _2embne _9138471
650		7	_aGenética animal _0 _2embne _9138513
700	1		_aDuggirala, Ravindranath _eeditor literario _994046 _0Local
700	1		_aAlmasy, Laura _eeditor literario _994047 _0Local
700	1		_aWilliams-Blangero, Sarah _eeditor literario _994048 _0Local
700	1		_aPaul, Solomon F.D _eeditor literario _994049 _0Local
700	1		_aKole, Chittaranjan _eeditor literario _948583 _0comprobar nb2006026533
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-662-46306-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12901568 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aQH445.2 G466 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11571184 _z06-04-17
999			_c81566 _d81566 _x1