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007			cr nn 008mamaa
008			141025s2015 gw | s |||| 0|eng d
020			_a9783662446089
024	7		_a10.1007/978-3-662-44608-9 _2doi
050		4	_aQL979 _b.V478 2015
245	1	0	_aVertebrate Myogenesis : _bStem Cells and Precursors _cedited by Beate Brand-Saberi.
260			_aBerlin, Heidelberg _bSpringer _c2015
300			_a1 recurso en línea (VI, 242 páginas) _b25 ilustraciones, 23 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aResults and Problems in Cell Differentiation _x0080-1844 _v56
505	0		_aRecruitment of skeletal muscle progenitors to secondary sites: A role for CXCR4/SDF-1 signaling in skeletal muscle development -- Hypaxial muscle - controversial classification and controversial data? Skeletal Myogenesis in the Zebrafish and its Implications for Muscle Disease Modeling -- Mechanisms of Myogenic Specification and Patterning -- The avian embryo as a model system for skeletal myogenesis -- Head Muscle Development -- The lateral plate mesoderm â€{u0860}novel source of skeletal muscle -- Regulation of skeletal muscle development and disease by microRNAs -- Adult skeletal muscle stem cells -- Dormancy and quiescence of skeletal muscle stem cells.
520	3		_aThis book addresses the differentiation control of skeletal muscle in different locations of the vertebrate body. Particular attention is paid to novel regulatory molecules and signals as well as toÂ{u4A25} heterogeneity of origin that have revealed a developmental overlap between skeletal and cardiac muscle. Different functional muscle groups are the product of the evolution of the vertebrate classes, making a phylogenetic comparison worthwhile for understanding the role of muscle stem cells and precursors in myogenesis. New insights into the hierarchy of transcription factors, particularly in the context of these different muscle groups come from detailed investigations of the spatio-temporal and regulatory relationships derived from mouse and zebrafish genetics and avian microsurgery. Importantly, epigenetic mechanisms that have surfaced recently, in particular the role of MyomiRs, are also surveyed. Regarding human patients, encouraging results have been generated that identify parallels between embryonic myogenesis and regenerating myofibers Â{u4A21}t share regulatory molecules. Interestingly, the heterogeneity in embryonic origins Â{uF9A0}skeletal muscle groups in the vertebrate including Â{u8D6D}ans Â{u2829}is paralleled by their different susceptibility to types of muscle dystrophies. The progress that has been made in the field of muscle stem cell biology, especially on Â{u3874}ellite cells, is outlined in this book by experts in the field. The authors review recent insights of the heterogeneous nature of these satellite cells regarding their gene signatures and regeneration potential. An improved understanding of muscle stem cells seems only possible with a view to the cell environment , putting embryological and molecular findings from different vertebrate classes and stem cell approaches into context.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		7	_aCitogenética _0 _2embne _9139622
650		7	_aProteínas _0 _2embne _9139861
650		7	_aCitología _0 _2embne _9139477
700	1		_aBrand-Saberi, Beate _eeditor literario _994035 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-662-44608-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12901465 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aQL979 .V478 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11571081 _z06-04-17
999			_c81556 _d81556 _x1