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020 _a9783662437841
024 7 _a10.1007/978-3-662-43784-1
_2doi
050 4 _aQH471
_b.M845 2015 EB
082 0 4 _a571.86
100 1 _aMueller, Werner A.
_994028
_0Local
245 1 0 _aDevelopment and Reproduction in Humans and Animal Model Species
_cby Werner A. Mueller, Monika Hassel, Maura Grealy
260 _aBerlin, Heidelberg
_bSpringer
_c2015
300 _a1 recurso en línea (XI, 725 p.)
_b322 ilustraciones, 317 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _aDevelopment and Reproduction: An Introduction -- Stages and Principles of Animal Development Terms of Developmental Biology -- The Start: Fertilization, Activation of the Egg and a First Series of Cell Divisions (Cleavage) -- Model Organisms in Developmental Biology I: Invertebrates -- Development of Important Model Species II: Vertebrates -- The Human -- In Preparation for New Life I: Sex Determination and Sexual Development -- In Preparation for New Life II: Gametogenesis: The Development of Egg Cells and Sperm and Their Provision with Heritable Reserves -- Specification of Body Axes and Localized Fate Allotment by External and Maternal Cues -- Positional Information, Embryonic Induction and Pattern Formation by Cell-Cell-Communication -- Controlling Signals, Signal Propagation and Signal Transduction -- Development and Genes -- Application- Oriented Experiments with Early Vertebrate Embryos: Cloning, Transgenic Animals -- Morphogenesis: Shaping by Active Cell Movement, Differential Cell Adhesion and Cell Death -- Long Distance Wanderers and the Various Fates of the Neural Crest Cells -- The Nervous System and Central Sensory Organs -- Heart and Blood Vessels -- Stem cells, Regeneration, Regenerative Medicine -- Growth Control and Cancer -- Metamorphosis and its Hormonal Control -- Immortality or Ageing and Death: What is Nature's Aim? -- Evolution of Development
520 3 _aThis book describes human development including sexual reproduction and stem cell research with the development of model organisms that are accessible to genetic and experimental analysis in readily understandable texts and 315 multi-colored graphics. The introductory account of model organisms selected from the entire animal kingdom presents general principles, which are then outlined in subsequent chapters devoted to, for example, sexual development; genes controlling development and their contemporary molecular-analysis methods; production of clones and transgenic animals; development of the nervous and circulatory systems; regenerative medicine and ageing. Finally the evolution of developmental toolkits and novelties is discussed including the genetic basis of the enlargement of the human forebrain. Separate boxes are devoted to controversial questions such as the benefits and problems of prenatal diagnostics or the construction of ancient body plans
710 2 _aSpringerLink (Online service)
_0Local
_9106996
942 _2lcc
_cLE
988 _aEBOOK, EBSPRINGER
650 7 _aReproducción
_9144703
_0comprobar BNE19913247411
_2embne
650 7 _aFisiología
_0comprobar BNE19900960421
_2embne
_9138487
700 1 _aHassel, Monika
_994029
_0Local
700 1 _aGrealy, Maura
_994030
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-662-43784-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783662437841
907 _a.b1290143x
_b10-11-17
_c18-01-16
998 _am
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_b10-11-17
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945 _aQH471 .M845 2015 EB
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