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007			cr nn 008mamaa
008			150603s2015 gw | s |||| 0|eng d
020			_a9783658101619
024	7		_a10.1007/978-3-658-10161-9 _2doi
050		4	_aRM301.9 _bA436 2015
100	1		_aAlborzinia, Hamed _0Local _994026
245	1	0	_aReal-Time Monitoring of Cancer Cell Metabolism for Drug Testing _cby Hamed Alborzinia.
260			_aWiesbaden _bSpringer _c2015
300			_a1 recurso en línea (XIII, 153 páginas) _b32 ilustraciones
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aDrug Screening with New Perspectives -- Real-Time Monitoring of Living Cells by a Novel Online Biosensor Chip -- Anticancer Agents â€{u0166}fects Measured in Real Time -- Metabolism of Cancer Cells.
520	3		_aHamed Alborzinia uses the biosensor chip to monitor the metabolic and morphological changes in cancer cell lines in real time, particularly: (i) real-time measurements of basic cancer cell metabolism of different cancer cell lines; (ii) a detailed timeline of the metabolic response to cisplatin treatment and clear detection of the time span between start of cisplatin treatment and onset of cell death, which reflects the time required for the underlying molecular mechanisms of cell fate decision; (iii) direct functional measurement of the biological activity of a key regulatory protein of cellular metabolism following the kinetic change in respiration upon SIRT3 overexpression; and (iv) the time-resolved impact of several organometallic compounds on cell metabolism and cell morphology, including unexpected and not yet understood highly significant and specific effects on cell-cell interaction and adhesion. Â{u3BEE}ntents Drug Screening with New Perspectives Real-Time Monitoring of Living Cells by a Novel Online Biosensor Chip Anticancer Agents â€{u0166}fects Measured in Real Time Metabolism of Cancer Cells Â{u4872}get Groups Researchers and students in the fields of biotechnology and pharmacy The Author Hamed Alborzinia graduated in veterinary medicine from Shiraz University (Iran) in 2005 and continued in the Ph.D. program, now as post-Doc, with Prof. Dr. Stefan WÃœlfl at Heidelberg University (IPMB), using bioanalytical techniques in research on cancer cell metabolism.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		7	_aAnálisis clínicos _2embne _9138438
650	2	7	_aFarmacología _2embne _9137893
650		7	_aFarmacología _2embne _9137893
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-658-10161-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12901416 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aRM301.9 A436 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11571032 _z06-04-17
999			_c81551 _d81551 _x1