000			03148nam a22003975i 4500
001			81518
003			ES-MaUEC
005			20230207040333.0
007			cr nn 008mamaa
008			150922s2015 gw | s |||| 0|eng d
020			_a9783319230788
024	7		_a10.1007/978-3-319-23078-8 _2doi
050		4	_aQP572.O74 _bO749 2015
245	1	0	_aOrexin and Sleep : _bMolecular, Functional and Clinical Aspects _cedited by Takeshi Sakurai, S.R. Pandi-Perumal, Jaime M. Monti.
250			_a1st ed. 2015.
260			_aCham, Switzerland _bSpringer _c2015
300			_a1 recurso en línea (XIV, 410 páginas) _b62 ilustraciones
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aHistory of Orexin Research -- The Hypocretin Story -- Input and output systems of orexin neurons -- Physiological roles of orexin receptors on sleep/wakefulness regulation -- Orexin receptor functions in the ascending arousal systemÂ{u81AF}lder name - Leonard) -- Elucidation of neuronal circuitry involved in the regulation of sleep/wakefulnessÂ{u5CE9}ng optogeneticsÂ{u81AF}lder name - Yamanaka) -- Modulation of thalamocortical pathways by orexins -- Orexins, Alcohol and Sleep Homeostasis -- Orexin induced modulation of REM sleep and its loss associated patho-physiological changes are mediated through locus coeruleus -- Role of orexin on sleep: interactions with other neurotransmitter systems.
520	3		_aThis volume is intended for neuropharmacologists, psychopharmacologists, pharmacologists, pharmacists, sleep researchers, translational neuroscience researchers, and otherÂ{u2873}ic researchers and clinical scientists interested in an interdisciplinary approach to sleep medicine. The level of the book is aiming at CNS researchers, drug development scientists, basic and clinical sleep researchers, as well as senior medical students and fellows in psychiatry and neurology. Orexin and Sleep provides a unique resource, giving a comprehensive and highly readable summary of the basic concepts in orexin biology and pharmacology along with clinical applications in sleep medicine in general, and narcolepsy in particular.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		7	_aBiología molecular _0 _2embne _9139103
650		0	_9146728 _aNeuroquímica _0
650		7	_aFarmacología _0 _2embne _9137893
700	1		_aSakurai, Takeshi _eeditor literario _993979 _0Local
700	1		_aPandi-Perumal, S.R _eeditor literario _984106 _0Local
700	1		_aMonti, Jaime M _eeditor literario _914746 _0comprobar BNE19923607545
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-23078-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12901088 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aQP572.O74 O749 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11570702 _z06-04-17
999			_c81518 _d81518 _x1