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008 151113s2015 gw | s |||| 0|eng d
020 _a9783319227115
024 7 _a10.1007/978-3-319-22711-5
_2doi
040 _aES-MaUEC
_cES-MaUEC
_dES-MaUEC
050 4 _aQP609.S47
_bT447 2015
245 1 4 _aThe Serpin Family :
_bProteins with Multiple Functions in Health and Disease
_cedited by Margarethe Geiger, Felix Wahlmüller, Margareta Furtmüller
250 _a1st ed. 2015.
260 _aCham, Switzerland
_bSpringer
_c2015
300 _a1 recurso en línea (VIII, 329 páginas)
_b26 ilustraciones, 20 ilustraciones en color
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _a1. Serpin Evolution and Genetics -- 2. Serpin Structure and Mechanism -- 3. New Serpins / New Functions of Serpins in Coagulation, Fibrinolysis, and Angiogenesis -- 4. Serpins in Development and Reproduction -- 5. Intracellular clade B serpins, intracellular functions of other serpins -- 6. Interaction of Serpins with Membrane-anchored Proteases -- 7. Serpins in Neurobiology -- 8. Serpins in Inflammation and Infectious Diseases -- 9. Cellular Proteostasis Systems Responsible for Orchestrating SERPIN Conformational Maturation and/or Disposal -- 10. SERPIN-related Diseases: Cellular Injury, Disease Modifiers, and Therapeutic Approaches -- 11. Serpins in Cancer -- 12. Non-mammalian Serpins -- 13. Serpins and Signal Transduction -- 14. Non-inhibitory serpins: structures and functions -- 15. (Patho)-physiology and/or novel functions of human serpins (in particular: vaspin) Serpins in animal models.
520 3 _aThe book provides an comprehensive overview on biology, genetics and cellular functions of serpins (serine protease inhibitors) in health and disease. With over 1000 members serpins are the most diverse family of protease inhibitors. Latest groundbreaking research findings are presented and broaden the understanding on inhibitory and non-inhibitory serpins, not only in mammalian organisms but also in insects, worms, plants and viruses.
650 7 _aBiología molecular
_2embne
_9139103
650 7 _aBioquímica clínica
_2embne
_9149316
650 7 _aProteínas
_2embne
_9139861
700 1 _aGeiger, Margarethe
_eeditor literario
_993970
_0Local
700 1 _aWahlmüller, Felix
_eeditor literario
_993971
_0Local
700 _aFurtmüller, Margareta
_eeditor literario
_993972
_0Local
710 2 _aSpringerLink (Online service)
_0Local
_9106996
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-22711-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b12901003
_b10-10-17
_c18-01-16
942 _2lcc
_cLE
945 _aQP609.S47 T447 2015 EB
_g1
_ieBOOK
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_y.i11570623
_z06-04-17
988 _aEBOOK, EBSPRINGER, asignarmaterias_11febrero
998 _am
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_cm
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