000			03553nam a22003855i 4500
710	2		_aSpringerLink (Online service) _0Local _9106996
999			_c81484 _d81484 _x1
001			81484
003			ES-MaUEC
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007			cr nn 008mamaa
008			151112s2015 gw | s |||| 0|eng d
020			_a9783319210308
024	7		_a10.1007/978-3-319-21030-8 _2doi
040			_aES-MaUEC
050		4	_aRC269.7 _bC363 2015
245	1	0	_aCancer Stem Cells: Emerging Concepts and Future Perspectives in Translational Oncology _cedited by Sadegh Babashah.
250			_a1st ed. 2015.
260			_aCham, Switzerland _bSpringer _c2015
300			_a1 recurso en línea (XXX, 560 páginas) _b41 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aPreface -- I. The Biology of Cancer Stem Cells -- Cancer Stem Cells: A Quick Walk through the Concepts -- Cytokine Networks and Cancer Stem Cells -- Implications of CXCR4/CXCL12 Interaction for Cancer Stem Cell Maintenance and Cancer Progression -- Non-coding RNAs in Cancer and Cancer Stem Cells. Self-renewal Pathways in Mammary Stem Cells and Carcinogenesis II. Cancer Stem Cells in Human Malignancies -- Breast Cancer Stem Cells -- Lung Cancer Stem Cells -- Colorectal Cancer Stem Cells -- Pancreatic Cancer Stem Cells -- Glioblastoma Cancer Stem Cells -- Head and Neck Cancer Stem -- Leukemic and Lymphoid Stem Cells -- Leukemic Stem Cells in Acute Lymphoblastic Leukemia -- III. Novel Approaches for Targeting Cancer Stem Cells -- Targeting Key Stemness-Related Pathways in Human Cancers -- Targeting Cancer Stem Cells and the Tumor Microenvironment -- Cancer Stem Cells and Chemoresistance: Strategies to Overcome Therapeutic Resistance -- Cancer Stem Cells and Tumor Radioresistance -- Therapeutic Implications of Cancer Stem Cell: Challenges and Opportunities in Translational Studies. Index.
520	3		_aThe concept of cancer stem cells has great clinical implications. This is due to the fact that small subpopulations of these cells have been identified in a variety of neoplastic conditions ranging from solid tumors to liquid malignancies. Although there are some huge gaps in our current understanding of the role played by cancer stem cells in cancer biology, a growing body of evidence provides strong support for the principal functions of these cells in tumorigenesis. This has represented the potential of cancer stem cells in the development of novel and innovative tools for the treatment of metastatic tumors. This book aims to offer a broad framework for obtaining insight into the state-of-the-art knowledge on cancer stem cell biology and highlight the therapeutic implications of these cells in the future of clinical oncology.
650		7	_aResistencia a los medicamentos _2embne _9146972
650		7	_aBiología molecular _2embne _9139103
650		7	_aGenética humana _2embne _9140562
700	1		_aBabashah, Sadegh _eeditor literario _985171 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-21030-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12900746 _b10-10-17 _c18-01-16
942			_2lcc _cLE
945			_aRC269.7 C363 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11570362 _z06-04-17
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0