| 000 | 03742nam a22004095i 4500 | ||
|---|---|---|---|
| 999 |
_c81480 _d81480 _x1 |
||
| 001 | 81480 | ||
| 003 | ES-MaUEC | ||
| 005 | 20230214040156.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 151104s2015 gw | s |||| 0|eng d | ||
| 020 | _a9783319208190 | ||
| 024 | 7 |
_a10.1007/978-3-319-20819-0 _2doi |
|
| 040 |
_aES-MaUEC _bspa |
||
| 050 | 4 |
_aQL757 _b.P384 2015 |
|
| 245 | 1 | 0 |
_aPathogen-Host Interactions : _bAntigenic Variation v. Somatic Adaptations _cedited by Ellen Hsu, Louis Du Pasquier. |
| 250 | _a1st ed. 2015. | ||
| 260 |
_aCham, Switzerland _bSpringer _c2015 |
||
| 300 |
_a1 recurso en línea (VIII, 336 páginas) _b35 ilustraciones, 26 ilustraciones en color |
||
| 336 |
_aTexto _btxt _2rdacontent |
||
| 337 |
_aelectrónico _bc _2rdamedia |
||
| 338 |
_arecurso electrónico _bcr _2rdacarrier |
||
| 490 | 0 |
_aResults and Problems in Cell Differentiation _x0080-1844 _v57 |
|
| 505 | 0 | _aEvolution of immunity and pathogens -- A host-pathogen interaction reduced to first principles: Antigenic variation in T. brucei -- Antigenic variation in Plasmodium falciparum -- Polymorphic mucin-like proteins in Schistosoma mansoni, a variable antigen and a key component of the compatibility between the schistosome and its snail host -- Fibrinogen-related proteins (FREP) in mollusks -- Somatic and germline diversification of a putative immunoreceptor within one phylum: Dscam in arthropods -- An immune effector system in the Protochordate gut sheds light on fundamental aspects of vertebrate immunity -- Variable lymphocyte receptors: a current view -- Antibody repertoire in fish -- Unique features of fish immune repertoires: particularities of the adaptive immunity within the largest group of vertebrates -- The evolution and structure of atypical T cell receptors -- Diversification of the primary antibody repertoire by AID-mediated gene conversion -- Antibody isotype switching in vertebrates. | |
| 520 | 3 | _aThis volume provides in-depth reviews of model systems that exemplify the arms race in host-pathogen interactions. Somatic adaptations are responsible for the individualization of biological responses to the environment, and the continual struggle between host immune systems and invading pathogens has given rise to corresponding processes that produce molecular variation. Whether in mollusks or human beings, various host somatic mechanisms have evolved independently, providing responses to counter rapidly-changing pathogens. The pathways they utilize can include non-heritable changes involving RNA and post-translational modifications, or changes that produce somatic DNA recombination and mutation. For infectious organisms such as protozoans and flatworms, antigenic variation is central to their survival strategy. Evolving the ability to evade the host immune system not only increases their chances of survival but is also necessary for successful re-infection within the host population. | |
| 650 | 0 |
_9139394 _aParasitología |
|
| 650 | 7 |
_aCitología _2embne _9139477 |
|
| 650 | 7 |
_aInmunología _2embne _9138330 |
|
| 700 | 1 |
_aHsu, Ellen _eeditor literario _993932 _0Local |
|
| 700 | 1 |
_aDu Pasquier, Louis _eeditor literario _993933 _0Local |
|
| 710 | 2 |
_aSpringerLink (Online service) _0Local _9106996 |
|
| 856 | 4 | 0 |
_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-20819-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
| 907 |
_a.b12900709 _b10-10-17 _c18-01-16 |
||
| 942 |
_2lcc _cLE |
||
| 945 |
_aQL757 .P384 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11570325 _z06-04-17 |
||
| 988 | _aEBOOK, EBSPRINGER, asignarmaterias_11febrero | ||
| 998 |
_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0 |
||