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008			151023s2015 gw | s |||| 0|eng d
020			_a9783319201498
024	7		_a10.1007/978-3-319-20149-8 _2doi
050		4	_aQH517 _b.E443 2015
245	1	0	_aElectrophysiology of Unconventional Channels and Pores _cedited by Anne H. Delcour.
250			_a1st ed. 2015.
260			_aCham, Switzerland _bSpringer _c2015
300			_a1 recurso en línea (XI, 385 páginas) _b86 ilustraciones, 38 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aSpringer Series in Biophysics _x0932-2353 _v18
505	0		_aPart I Mitochondria -- Function and regulation of mitochondrial voltage-dependent anion channel -- Mitochondrial Protein Import Channels -- Electrophysiology of the mitochondrial apoptosis-induced channel, MAC -- Ceramide Channels -- Part II Bacteria and viruses -- Bacterial Porins -- Electrophysiology of Bacterial Translocons -- Viroporins -- Part III Toxins and antimicrobial peptides -- Pore-forming colicins- unusual ion channels -unusually regulated -- Anthrax Toxin Protective Antigen Forms an Unusual Channel that Unfolds and Translocates Proteins Across Membranes -- Staphylococcal b-barrel Pore-forming Toxins: Mushrooms That Breach the Greasy Barrier -- Properties of pores formed by cholesterol-dependent cytolysins and actinoporins -- Part IV Other unconventional channels -- Perforins -- Gap Junction Channels: The electrical conduit of the intercellular world -- Amyloid Peptide Channels -- From phototaxis to biomedical applications: Investigating the molecular mechanism of channelrhodopsins.
520	3		_aThis book is dedicated to the channels and pores that belong to an eclectic and ubiquitous class of unconventional - perhaps at times strange - pore-forming molecules, which nevertheless play fundamental roles in various organisms. These non-canonical channels may take on various and sometimes complex architectures, such as large beta-barrels or lipid-containing pores. They may originate from bacteria, viruses or intracellular organelles. For some of them, the physiologically relevant substrate may indeed be ions, and for others folded polypeptides. Some are released by cells in a soluble form that has the ability to insert into biological membranes to exert its permeabilizing effect. Many of these unconventional pores have been investigated by electrophysiology, which, by its virtue of focusing on a few or even a single unit, has provided invaluable insight into the mechanisms and structure-function relationships of these remarkable membrane entities. The chapters of this book highlight a representative set of these interesting investigations.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		7	_aProteínas _0 _2embne _9139861
650		7	_aMembranas celulares _0 _2embne _9142266
650		7	_aBiología _0 _2embne _9138150
700	1		_aDelcour, Anne H. _eeditor literario _0Local _993903
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-20149-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12900515 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aQH517 .E443 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11570131 _z06-04-17
999			_c81461 _d81461 _x1