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001			81451
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007			cr nn 008mamaa
008			151127s2015 gw | s |||| 0|eng d
020			_a9783319199207
024	7		_a10.1007/978-3-319-19920-7 _2doi
050		4	_aQD431 _b.B893 2015
100	1		_aBuxbaum, Engelbert _0Local _974027
245	1	0	_aFundamentals of Protein Structure and Function _cby Engelbert Buxbaum.
250			_a2nd ed. 2015.
260			_aCham, Switzerland _bSpringer _c2015
300			_a1 recurso en línea (XVI, 521 páginas) _b246 ilustraciones, 223 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aPart I: Proteins -- Amino Acids -- Protein Structure -- Proteins in the Lab -- Part II: Enzymes -- Enzymes are Biocatalysts -- Enzyme Kinetics and Mechanism -- Inhibition and Inactivation of Enzymes -- HÃ{uDE6F}globin and Myoglobin: Cooperativity -- Enzyme Kinetics: Special Cases -- The Flow of Metabolites through Metabolic Pathways -- Part III: Special Proteins -- Protein Folding Diseases -- Immunoproteins -- Cell Skeleton -- Motor Proteins and Movement -- Cell-cell interactions -- Aiding in Folding: Molecular Chaperones and Chaperonins -- Part IV: Membrane Transport -- Protein Transport across Membranes -- Vesicular Transport in Eukaryotic Cells -- Transport of Solutes across Membranes -- Appendices.
520	3		_aThis book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is explained. This leads to a discussion ofÂ{u8BF7} misfolding of proteins causes diseases like cancer, various encephalopathies, or diabetes. Enzymology and modern concepts of enzyme kinetics are then introduced, taking into account the physiological, pharmacological, and medical significance of this often neglected topic. This is followed by thorough coverage of hÃ{uDBE7}lobin and myoglobin, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins to various cell compartments, and solute transport across biological membranes. Proteins in the laboratory are also covered, including a detailed description of Â{u4A25} purification and determination of proteins, as well as their characterisation for size and shape, structure, and molecular interactions. The book emphasises the link between protein structure, physiological function, and medical significance. This book can be used for graduate and advanced undergraduate classes covering protein structure and function and as an introductory text for researchers in protein biochemistry, molecular and cell biology, chemistry, biophysics, biomedicine, and related courses. About the author: Dr. Buxbaum is a biochemist with anÂ{u9BB4}erest in enzymology and protein science. He has been working on the biochemistry of membrane transport proteins for nearly thirty years and has taught courses in biochemistry and biomedicine at several universities.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		7	_aQuímica _2embne _9137894
650		7	_aCitología _2embne _9139477
650		7	_aBiofísica _2embne _9139082
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-19920-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12900412 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aQD431 .B893 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11570039 _z06-04-17
999			_c81451 _d81451 _x1