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007			cr nn 008mamaa
008			150930s2015 gw | s |||| 0|eng d
020			_a9783319190969
024	7		_a10.1007/978-3-319-19096-9 _2doi
050		4	_aRA1211 _b.S783 2015
245	1	0	_aStudies on Experimental Toxicology and Pharmacology _cedited by Stephen M. Roberts, James P. Kehrer, Lars-Oliver Klotz.
250			_a1st ed. 2015.
260			_aCham _bSpringer International Publishing _bImprint: Humana Press _c2015.
300			_a1 recurso en línea (XVI, 498 páginas) _b96 ilustraciones, 53 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aOxidative Stress in Applied Basic Research and Clinical Practice _x2197-7224
505	0		_aPart I. Toxicological Mechanisms and Evaluation of Oxidative Stress -- A historical perspective on oxidative stress and intracellular redox control -- An overview of free radicals as causes and consequences of toxicity -- Oxidants, radicals, free radicals, and other bad stuff in mechanisms of toxicity -- Lipid oxidation -- Protein oxidation and toxicology -- Oxidative stress and DNA damage association with carcinogenesis: A truth or a myth? -- Glutathione and thiols -- Reactive oxygen species as initiators and mediators of cellular signaling processes -- Role of oxidative stress in the process of carcinogenesis -- Part II. Agents that produce toxicity â€{u0B65}chanisms and therapeutic interventions -- Isolation of murine adult bone marrow and fetal liver cells for mechanistic assessment of hematotoxicity caused by organic solvents -- Oxidative stress and ethanol toxicity -- Pharmaceutical agents -- Insecticides and herbicides -- Health effects of indoor air pollution due to cooking with biomass fuel -- Outdoor pollutants -- Oxidative Stress and the Inorganic Carcinogens -- UV-induced signaling: Role of reactive oxygen species -- Nanomaterials -- Chemical warfare agents -- Part III. Special topics -- On the biochemistry of antioxidants â€{u08F5}rrent aspects.-Prevention of age-related diseases â€{u0166}fects of antioxidant supplements -- The neural progenitor cell (NPC) niche in the adult brain provides a target for neurotoxicity â€{u0860}potential Adverse Outcome Pathway for ROS-induced NPC dysfunction with higher sensitivity during aging. -- Oxygen toxicity: From cough to convulsion -- Oxidative stress in reproductive toxicology -- Toxicogenomics-based assessment of xenobiotic-induced oxidative stress -- Aquatic and marine biology.
520	3		_aThis book focuses on data describing the roles of free radicals and related reactive species, and antioxidants, in the causes and treatments of diseases, examining both clinical and pre-clinical trials, as well as basic research. The book is divided into sub-sections with chapters on toxicological mechanisms, agents that produce toxicity, and special topics including areas such as antioxidant supplements, oxygen toxicity, toxicogenomics, and marine biology. Studies on Experimental Toxicology and Pharmacology promotes the concept of using biomarkers of free radical- and reactive species-induced injury as adjuncts to classical laboratory testing and the ability of antioxidants to provide cellular protection. There is increasing evidence that free radicals and other reactive species are causative, or at least supporting factors, that impact organisms and cause numerous tissue disorders. With contributions from international experts in the field, this volume is a valuable resource for researchers and postgraduate students in toxicology and related fields, as well as clinicians and clinical researchers.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		7	_aApoptosis. _9157983 _2embne
650		7	_aEstrés oxidativo _2embne _9158905
650		7	_aFarmacología _2embne _9137893
700	1		_aRoberts, Stephen M _eeditor literario _993865 _0Local
700	1		_aKehrer, James P. _eeditor literario _0Local _993866
700	1		_aKlotz, Lars-Oliver _eeditor literario _993867 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-19096-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b1290031x _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aRA1211 .S783 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11569931 _z06-04-17
999			_c81441 _d81441 _x1