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020 _a9783319186030
024 7 _a10.1007/978-3-319-18603-0
_2doi
050 4 _aQP517.S87
_bI468 2015
245 1 0 _aImmune Responses to Biosurfaces :
_bMechanisms and Therapeutic Interventions
_cedited by John D. Lambris, Kristina N. Ekdahl, Daniel Ricklin, Bo Nilsson.
250 _a1st ed. 2015.
260 _aCham, Switzerland
_bSpringer
_c2015
300 _a1 recurso en línea (XII, 242 páginas)
_b34 ilustraciones, 28 ilustraciones en color
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aAdvances in Experimental Medicine and Biology
_x0065-2598
_v865
505 0 _aPart 1. Mechanisms -- Thromboinflammation in Therapeutic Medicine -- Complement Interactions with Blood Cells, Endothelial Cells and Microvesicles in Thrombotic and Inflammatory Conditions -- Role of Complement on Broken Surfaces after Trauma -- Complement Involvement in Periodontitis: Molecular Mechanisms and Rational Therapeutic Approaches -- Part 2. Biomaterials -- The Lectin Pathway of Complement and Biocompatibility -- Foreign Body Reaction to Subcutaneous Implants -- Molecular Characterization of Macrophage-Biomaterial Interactions -- Heparan Sulfate Proteoglycan Metabolism and the Fate of Grafted Tissues -- Part 3. Transplantation -- Xenotransplantation of Cells, Tissues, Organs and the German Research Foundation Transregio Collaborative Research Centre 127 -- Macro encapsulated Pig Islets Correct Induced Diabetes in Primates up to 6 Months -- Regulation of Instant Blood Mediated Inflammatory Reaction (IBMIR) in Pancreatic Islet Xeno-Transplantationâ€{u0BE9}nts for Therapeutic Interventions -- Cell Surface Engineering for Regulation of Immune Reactions in Cell Therapy -- Complement Interception Across Humoral Incompatibility in Solid Organ Transplantationâ€{u1803}linical Perspective.
520 3 _aThe collection of chapters in this proceedings volume brings together research from academic and industry scientists and clinical development experts who are focused on contemporary and emerging aspects of improving treatments employing biosurfaces. Interactions between biomaterial implants, devices, cell therapies, and whole organ transplants frequently trigger activation of body defense systems and responses that negatively affect the clinical outcome. Optimal tissue integration and modulation of foreign body reactions is therefore essential for preserving anticipated functions and avoiding adverse effects. Topics covered include mechanistic and applied research within the fields of extracorporeal devices, soft and hard tissue implants, tissue and biomaterial-targeting, therapeutic modulation of foreign body reactions, cell encapsulations, as well as cell and whole organ transplantation.
710 2 _aSpringerLink (Online service)
_0Local
_9106996
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988 _aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650 7 _aBiotecnología
_2embne
_9140931
650 7 _aInmunología
_2embne
_9138330
650 2 7 _aInmunología
_2embne
_9138330
700 1 _aLambris, John D.
_eeditor literario
_0Local
_984215
700 1 _aEkdahl, Kristina N.
_eeditor literario
_0Local
_993854
700 1 _aRicklin, Daniel
_eeditor literario
_984543
_0Local
700 1 _aNilsson, Bo
_eeditor literario
_924284
_0comprobar BNE19961865998
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-18603-0
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b12900217
_b10-10-17
_c18-01-16
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