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007			cr nn 008mamaa
008			150811s2015 gw | s |||| 0|eng d
020			_a9783319183145
024	7		_a10.1007/978-3-319-18314-5 _2doi
050		4	_aRB155.5 _bS746 2015
245	1	0	_aStem Cells in Modeling Human Genetic Diseases _cedited by Mayana Zatz, Oswaldo Keith Okamoto.
250			_a1st ed. 2015.
260			_aCham, Switzerland _bSpringer _c2015
300			_a1 recurso en línea (XII, 147 páginas) _b16 ilustraciones, 15 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aStem Cell Biology and Regenerative Medicine _x2196-8985
505	0		_aModeling Fragile X Syndrome in Human Pluripotent Cells -- Induced Pluripotent Stem Cells in Familial Dilated Cardiomyopathy.-Â{u9BA4}duced Pluripotent Stem Cells and Amyotrophic Lateral Sclerosis -- IPS Cells and Spinocerebellar Ataxia -- Induced Pluripotent Stem Cells and Vascular Disease -- iPS Cells and Cardiomyopathies -- Cancer Stem Cells and Chemoresistance -- Stem Cells in Autism Spectrum Disorders.
520	3		_aUsing stem cells to investigate currently untreatable human genetic diseases is the focus of this book. Several applications of the Nobel-Prize winning, revolutionary iPS cell technology are explored in detail, including in schizophrenia, autism, Huntingtonâ€{u3824}isease, Alzheimerâ€{u3824}isease, spinocerebellar ataxia, medulloblastoma heterogeneity, progeria, age-related macular degeneration, and muscular dystrophy . The book is divided into seven sections, each composed of authoritative and detailed chapters. The first section provides a theoretical and practical overview of stem cells in disease modeling. The following sections divide stem cell applications into various classes of pathology- Â{u0CF9}chiatric disorders, neurodegenerative disease, neurogenesis-associated disorders, and laminopathies. Following these sections, the book discusses the future perspectives- and challenges- of iPS technology.Â{u2820} Broad in scope and in audience, Stem Cells in Modeling Human Genetic Diseases Â{u6BF2} postgraduate students, scientists, and clinicians interested in applications of the rapidly developing field of stem cell research in disease modeling and drug development and its dynamic role within regenerative medicine.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		7	_aCélulas madre _0 _2embne _9160528
650		7	_aMedicina regenerativa _0 _2embne _9678347
650		7	_aGenética humana _0 _2embne _9140562
700	1		_aZatz, Mayana _eeditor literario _993825 _0Local
700	1		_aKeith Okamoto, Oswaldo _eeditor literario _993826 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-18314-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12900102 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aRB155.5 S746 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11569724 _z06-04-17
999			_c81420 _d81420 _x1