000			03878nam a22003615i 4500
001			81415
003			ES-MaUEC
005			20230207040329.0
007			cr nn 008mamaa
008			150917s2015 gw | s |||| 0|eng d
020			_a9783319179421
024	7		_a10.1007/978-3-319-17942-1 _2doi
050		4	_aQH447 _b.G466 2015
245	1	0	_aGenomics, Personalized Medicine and Oral Disease _cedited by Stephen T. Sonis, DMD, DMSc.
250			_a1st ed. 2015.
260			_aCham, Switzerland _bSpringer _c2015
300			_a1 recurso en línea (XIV, 408 páginas) _b47 ilustraciones, 36 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aFundamentals of genetics, genomics, and personalized medicine -- Current and evolving genomic-based technologies. The oral micro biome, translational genomics and personalized medicine: the future -- Host genetics and response to HerpesÂ{u3A6D}plex type I infection -- OrofacialÂ{u3B25}fts: the promise of personalized medicine for developmental anomalies -- Genetics and genomic studies of dental caries: insights into the promise of personalized medicine -- Periodontal disease -- Recurrent aphthous stomatitis puzzle in the era of the omic technologies -- Genomics and bioinformatics of oral lichen planus (OLP) -- Pemphigoid disease -- Salivary gland diseases -- Insights into oral epithelial premalignancy from the genetic/epigenetic viewpoints -- Oral cancer -- Medication-induced osteonecrosis of the jaw (MIONJ) -- Developing a gene therapy for radiation-induced dry mouth -- Radiation protection of the oral cavity/oropharynx: antioxidant strategies from MnSOD-plasmid liposomes to GS-nitroxides -- Pharmacogenomics and oral diseases -- Genetically modified Lactococcus lactis: a novel engineering system for mucosal delivery.-Â{u0972}sonalized medicine, genomics and oral diseases: the future.
520	3		_aThe objective of this book is to catalyze the application of genomics to the diagnosis and treatment of oral diseases by comprehensively presenting focused discussions on the current state of knowledge. The first section of the book provides basic information about genetics, genomics, and personalized medicine and the informatical methods available to apply and organize genetic data so that it has clinical relevance. Recognizing the genetic robustness of the oral cavity, the introductory section includes chapters on the oral microbiome and host genomics and response to infectious agents. The next two sections contain chapters which describe the genomics of specific oral diseases and conditions, including the genetic basis for mechanism and risk of treatment toxicities associated with cancer therapy and bisphosphonates. Four chapters focus on gene-based therapies and the pharmacogenomics applied to oral disease. The final chapter presents a provocative summary which describes a comprehensive vision of the melding of genomics to personalized medicine and the potential actionable outcomes that will likely affect clinical practice in the upcoming years.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, asignarmaterias, EBSPRINGER,
650		7	_aGenética humana _2embne _9140562
650	2	7	_aGenética humana _2embne _9140562
700	1		_aSonis, Stephen T. _eeditor literario _0Local _966964
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-17942-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12900059 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aQH447 .G466 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11569670 _z06-04-17
999			_c81415 _d81415 _x1