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001			81393
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007			cr nn 008mamaa
008			150420s2015 gw | s |||| 0|eng d
020			_a9783319165370
024	7		_a10.1007/978-3-319-16537-0 _2doi
050		4	_aQH588.S83 _bS746 2015
245	1	0	_aStem Cell Biology in Neoplasms of the Central Nervous System _cedited by Moneeb Ehtesham.
260			_aCham, Switzerland _bSpringer _c2015
300			_a1 recurso en línea (XIII, 190 páginas) _b16 ilustraciones, 15 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v853
505	0		_aRegulation of Subventricular Zone-Derived Cells Migration in the Adult Brain -- TheÂ{u3583} and Its Relationship to Stem Cell Based Neuro-oncogenesis. - Isolation and characterization of stem cells for human central nervous system malignancies. - The role of stem cells in pediatric central nervous system malignancies. - Laboratory models for central nervous system tumor stem cell research. - Radiation Therapy for Glioma Stem Cells -- Chemoresistance and chemotherapy targeting stem-like cells in malignant glioma -- Immunobiology and Immunotherapeutic targeting of glioma stem cells -- Emerging strategies for the treatment of tumor stem cells in central nervous system malignancies.
520	3		_aThis volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used. The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. Importantly, the realization that a distinct sub-population of cells contributes disproportionately to the growth and sustenance of central nervous system tumors has important implications for the treatment of such tumors. To treat CNS tumors, there is now a growing need to treat CSCs to achieve adequate tumor control.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		7	_aCélulas madre _2embne _9160528
650	2	7	_aCélulas madre _2embne _9160528
650		7	_aNeurociencias _2embne _9158907
700	1		_aEhtesham, Moneeb _eeditor literario _993787 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-16537-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12899835 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aQH588.S83 S746 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11569451 _z06-04-17
999			_c81393 _d81393 _x1