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008			150429s2015 gw | s |||| 0|eng d
020			_a9783319161044
024	7		_a10.1007/978-3-319-16104-4 _2doi
040			_dES-MaUEC
050		4	_aTP248.65 _bT445 2015
245	1	4	_aThe Impact of Food Bioactives on Health : _bin vitro and ex vivo models _cedited by Kitty Verhoeckx, Paul Cotter, Iván López-Expósito, Charlotte Kleiveland, Tor Lea, Alan Mackie, Teresa Requena, Dominika Swiatecka, Harry Wichers
260			_aCham, Switzerland _bSpringer _c2015
300			_a1 recurso en línea (XVII, 338 páginas) _b57 ilustraciones, 35 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aIntroduction -- Gastrointestinal digestion models, general introduction -- Static digestion models general introduction -- InfoGest consensus method -- Approaches to static digestion models -- Dynamic digestion models general introduction -- The TNO gastro-Intestinal Model (TIM) -- Dynamic Gastric Model (DGM) -- Human Gastric Simulator (Riddet model) -- The DIDGI® System -- General introduction to cells, cell lines and cell culture -- Epithelial cell models; General introduction -- Caco-2 cell line -- HT29 cell line -- The IPEC-J2 cell line -- Co-cultivation of Caco-2 and HT-29MT -- Innate and adaptive immune cells; General introduction -- THP-1 and U937 cells -- Peripheral blood mononuclear cells -- PBMC-derived T cells -- Dendritic Cells -- Co-culture Caco-2/ immune cells -- Enteroendocrine Cell Models: General introduction -- STC-1 cells -- NCI-H716 cells -- Murine GLUTag cells -- In vitro intestinal tissue models: General introduction -- Intestinal crypt organoids as experimental models -- Porcine ex vivo intestinal segment model -- Ussing chamber -- In vitro fermentation models: General Introduction -- One compartment fermentation model -- The TNO in vitro model of the colon - TIM-2 -- The Simulator of the Human Intestinal Microbial Ecosystem â€{u04C8}IME® -- The computer-controlled multicompartmental dynamic model of the gastrointestinal system SIMGI.
506	0		_aOpen Access
520	3		_aThis book describes in vitro and ex vivo models that can be employed to investigate effects of digested food products on the GIT, or specific components thereof. Many such models exist and include, for example, those used to study digestion and fermentation in the small and large intestine, to investigate absorption (e.g. Ussing chamber, epithelial cell systems), and to research the immune and enteroendocrine responses (e.g. macrophages, dendritic cells, co-cultures). In each case, these respective assays and models are discussed, and tips and tricks concerning their proper use are given. The Impact of Food Bioactives on Health: In Vitro and Ex Vivo Models is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest. The book highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated, and highlights the strengths and weaknesses of the various assays. It is also an important resource for under-graduate students in the 'food and health' arena.
650		0	_9158790 _aBiotecnología alimentaria
650	2	7	_aMicrobiología alimentaria _2embne _9150782
650		7	_aFisiología humana _2embne _9140024
700	1		_aVerhoeckx, Kitty _eeditor literario _993759 _0Local
700	1		_aCotter, Paul _eeditor literario _993760 _0Local
700	1		_aLópez-Expósito, Iván _eeditor literario _993761 _0Local
700	1		_aKleiveland, Charlotte _eeditor literario _993762 _0Local
700	1		_aLea, Tor _eeditor literario _993763 _0Local
700	1		_aMackie, Alan _eeditor literario _993764 _0Local
700	1		_aRequena, Teresa _eeditor literario _993765 _0Local
700	1		_aSwiatecka, Dominika _eeditor literario _993766 _0Local
700	1		_aWichers, Harry _eeditor literario _993767 _0Local
710	2		_aSpringerLink (Online service) _0Local _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-16104-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12899720 _b10-10-17 _c18-01-16
942			_2lcc _cLE
945			_aTP248.65 T445 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11569347 _z06-04-17
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h4