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008			150425s2015 gw | s |||| 0|eng d
020			_a9783319158112
024	7		_a10.1007/978-3-319-15811-2 _2doi
050		4	_aRC268.4 _b.N498 2015 EB
082	0	4	_a614.5999
245	0	0	_aNext Generation Sequencing in Cancer Research, Volume 2 : _bFrom Basepairs to Bedsides _cedited by Wei Wu, Hani Choudhry
260			_aCham, Switzerland _bSpringer _c2015
300			_a1 recurso en línea (XVIII, 493 p.) _b78 ilustraciones, 70 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aSingle-cell next Generation Sequencing and Its Applications in Cancer Biology -- Utility of Next Generation Sequencing in Cancer Drug Development and Clinical Trials -- Next-Generation Sequencing in the Era of Cancer-Targeted Therapies: Towards the Personalised Medicine -- Mutational Similarities Across Cancers: Implications for Research, Diagnostics and Personalized Therapy Design -- Standardized Decision Support in NGS Reports of Somatic Cancer Variants -- Clinical Considerations in the Conduct of Cancer Next Generation Sequencing Testing and Genetic Counselling -- Next Generation Sequencing for Cancer Biomarker Discovery -- Validation and Implementation of Next Generation Sequencing Technologies in a Clinical Molecular Diagnostic Laboratory -- Next Generation Sequencing Technologies and Formalin Fixed Paraffin Embedded Tissue: Application to Clinical Cancer Research -- Applications of NGS to Screen FFPE Tumours for Detecting Fusion Transcripts -- Clinical Application of Next-Generation Sequencing of Formalin-Fixed Paraffin-Embedded Tumors -- ChIP-BS-Sequencing in Cancer Epigenomics -- Integrative Analysis Identifies Transcription Factor-DNA Methylation Relationships and Introduces New Avenues for Translating Cancer Epigenetics Into the Clinic -- Differential Methylation Analysis with Next-Generation Sequencing -- Performance Comparison and Data Analysis Strategies for MicroRNA Profiling in Cancer Research -- Small RNA Sequencing for Squamous Cell Carcinoma Research -- Exome Capture and Capturing Technologies in Cancer Research -- The Landscape of DNA Virus Associations Across Human Malignant Cancers -- Using Next Generation Sequencing to Reveal Patterns of Chromosomal Alterations in Oral Verrucous Carcinoma -- Vironomics: The Study of Viral Genomics in Human Cancer and Disease -- Molecular Typing of Lung Adenocarcinoma on Cytological Samples in the Next Generation Sequencing Era -- Whole Genome/Exome Sequencing in Acute Leukemia: From Research to Clinics -- Next Generation Sequencing Applications in Head and Neck Oncology -- CIC Mutation in Brain Tumor -- Isocitrate Dehydrogenase (IDH) Mutation in Gliomas -- Utilization of Multigene Panels in Hereditary Cancer Predisposition Testing.
520	3		_aNext Generation Sequencing in Cancer Research, Volume 2: From Basepairs to Bedsides, the second in the series- Next Generation Sequencing Technology in Cancer Research Basepairs to Bedsides, designed to fill the gap between cancer genome research and clinical management of the individual cancer patient. The volume presents the principles of next generation sequencing (NGS) technologies and massively parallel DNA sequencing and their application of the whole genome sequences (WGS), whole exome-seq (WES), RNA-seq, miRNA-seq, and ChIP-seq in cancer research programs and to apply the newly discovered driver genetic alterations for prevention, early diagnosis and genome-oriented precision cancer treatment. Next Generation Sequencing in Cancer Research, Volume 2: From Basepairs to Bedsides brings together the implementation of a wide range of NGS technologies, including single-cell sequencing, in the clinical setting: discovery and validation of cancer biomarkers; standardization of NGS data production; NGS data reporting systems for clinicians; novel anti-cancer therapies Development from NGS data; conducting of clinical trials of newly investigated cancer drugs. It provides compelling evidence to signal a new future for health care and a new standard for cancer care
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER
650		7	_aCáncer _xAspectos genéticos _9273952 _0comprobar BNE19990911214 _2embne
700	1		_aWu, Wei _eeditor literario _944479
700	1		_aChoudhry, Hani _eeditor literario _984778 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-15811-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319158112
907			_a.b12899653 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b09-08-17 _cm _dz _ek _feng _ggw _h0
945			_aRC268.4 N498 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i1156927x _z06-04-17
999			_c81375 _d81375 _x1