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001			81369
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007			cr nn 008mamaa
008			150414s2015 gw | s |||| 0|eng d
020			_a9783319155180
024	7		_a10.1007/978-3-319-15518-0 _2doi
050		4	_aTD196.F55 _bT695 2015
245	1	0	_aToxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances _cedited by Jamie C. DeWitt.
260			_aCham _bSpringer International Publishing _bImprint: Humana Press _c2015.
300			_a1 recurso en línea (XIII, 495 páginas) _b49 ilustraciones, 15 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aMolecular and Integrative Toxicology _x2168-4219
505	0		_aPerfluorinated compounds: An overview -- Analysis of PFASs in biological tissues and fluids -- PFASs in the general population -- PFAS Biomonitoring in Higher Exposed Populations -- Perfluorinated Alkyl Acids in Wildlife -- Metabolism and Pharmacokinetics -- Metabolic EffectsPFAS -- Developmental Toxicity -- Neurotoxicity -- Immunotoxicity of Perfluoroalkylated Compounds -- Effects of PFOA on Endocrine-related Systems -- Carcinogenicity of Perfluoroalkyl Compounds -- Epidemiological Findings -- Dosimetric Anchoring of Toxicological Studies -- Human Health Risk Assessment of Perfluoroalkyl Acids -- Systematic Review, An Illustration of Increased Transparency in a Framework for Evaluating Immunotoxicity Associated with PFOA and PFOS Exposure -- Toxicology data for alternative “short-chainâ€{u09AC}uorinated substances -- Conclusions and recommendations.Â{u282E}.
520	3		_aThis book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances (PFASs), covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms. This book includes chapters on human and wildlife exposure/body burdens, reviews of metabolism and toxicological effects by organ system/developmental stage, and aspects of PFAS toxicity that are driving PFAS research and regulatory oversight. Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances provides critical assessments of the most controversial topics surrounding toxicological evaluation of PFASs to give readers an expert perspective on the issues. Emphasis is placed on the integration of modes and mechanisms of action with functional endpoints that are relevant to human and wildlife health. This book will be a useful resource for toxicologists, environmental chemists, risk assessors, and researchers with an interest in the class of compounds known as perfluoroalkyl and polyfluoroalkyl substances.
710	2		_aSpringerLink (Online service) _0Local _9106996
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650		7	_aHigiene ambiental _0 _2embne _9138430
650		7	_aToxicología ambiental _0 _2embne _9159275
650		7	_aFarmacología _0 _2embne _9137893
700	1		_aDeWitt, Jamie C. _eeditor literario _0Local _993740
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-15518-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12899598 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0
945			_aTD196.F55 T695 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11569219 _z06-04-17
999			_c81369 _d81369 _x1