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020 _a9783319150635
024 7 _a10.1007/978-3-319-15063-5
_2doi
050 4 _aRC387.5
_bC455 2015
245 1 0 _aCell Therapy for Brain Injury
_cedited by David C. Hess.
260 _aCham, Switzerland
_bSpringer
_c2015
300 _a1 recurso en línea (XI, 369 páginas)
_b41 ilustraciones, 35 ilustraciones en color
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _aIntroduction to Cell Therapy in Brain Injury -- Cell Based Therapeutics in Stroke: An Industry Perspective -- Autologous Mesenchymal Stem Cell Therapy in Patients with Stroke -- Treatment of Autologous Bone Marrow Mononuclear Cells for Acute and Subacute Stroke: Cell-Therapy for Acute/Subacute Stroke -- Clinical Development of MultiStem® for Treatment of Injuries and Diseases of the Central Nervous System -- Intra-Arterial Approaches to Stem Cell Therapy for Ischemic Stroke -- Neural Stem Cells in Stroke: Intracerebral Approaches -- The CTX Human Neural Stem Cell Line and the PISCES Stroke Trial -- Induced Pluripotent Stem Cells as a Cell-based Therapeutic in Stroke -- Induced Pluripotent Stem Cell Derived Neural Cell Types In Treatment of Stroke -- Preconditioning and Cell-based Therapeutics -- Tracking of Administered Progenitor Cells in Brain Injury and Stroke by Magnetic Resonance Imaging -- Biomaterials Application in Stem Cell Therapies for Stroke -- A Stem Cell Derived Cell-Free Therapy for Stroke: Moving Conditioned Medium into Clinical Trial -- Pathophysiology of Traumatic Brain Injury: Rationale and Role for Cellular Therapies -- Stem Cell Therapy for Neonatal Hypoxic-Ischemic Brain Injury -- Cell-Based Therapies in Neonatal Stroke -- Issues in Clinical Trial Design in Stem Cell Trials after Stroke.
520 3 _aThis is a review of state-of-the-art cell therapy in the treatment of stroke, traumatic brain injuries and neonatal stroke and hypoxia-ischemia using a variety of cells ranging from bone marrow derived stem cells and mesenchymal stem cells to induced pluripotent stem cells derived neural progenitors.This invaluable book covers this niche topic in depth from basic stem cell biology and principles of cell therapy through proposed mechanisms of action of cell therapy in stroke, pre-clinical data in stroke models, ongoing clinical trials, imaging and tracking of cells with MRI, neural stem cells in stroke, approaches using conditioned medium, and the "big pharma" perspective of cell therapy. Each of eighteen chapters has been contributed by a well-known leader in each field, thus providing a wealth of international perspective and expertise. Cell Therapy for Brain Injuryâ€{u3822}readth makes it essential reading for neuroscientists, stem cell biologists, researchers or clinical trialists at pharmaceutical or biotechnology companies. It also serves as a thorough introduction for graduate students or post-doctoral fellows who hope to work in these fields.
710 2 _aSpringerLink (Online service)
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_9106996
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988 _aEBOOK, EBSPRINGER, asignarmaterias_11febrero
650 7 _aCélulas madre
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650 7 _aNeurociencias
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_2embne
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650 7 _aNeurocirugía
_0
_2embne
_9141879
700 1 _aHess, David C.
_eeditor literario
_0Local
_993734
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-15063-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b12899525
_b10-10-17
_c18-01-16
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