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020 _a9783319139395
024 7 _a10.1007/978-3-319-13939-5
_2doi
050 4 _aRC365
_b.T695 2015 EB
082 0 4 _a612.8042
245 1 0 _aToxicity and Autophagy in Neurodegenerative Disorders
_cedited by José M. Fuentes
260 _aCham, Switzerland
_bSpringer
_c2015
300 _a1 recurso en línea (XV, 268 p.)
_b34 ilustraciones, 27 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 1 _aCurrent Topics in Neurotoxicity
_x2363-9563
_v9
505 0 _aRegulation of Autophagy In Health And Disease -- Role of Chaperone-Mediated Autophagy in Ageing and Neurodegeneration -- Interaction Between Mitochondria And Autophagy -- Dual role of autophagy in neurodegenerative diseases: The case of amyotrophic lateral sclerosis -- Autophagy pathways in Huntingtonþs disease -- Control of Autophagy in Parkinsonþs Disease -- Autophagy in Alzheimerþs disease: a cleaning service out-of-order? -- Autophagy as a neuroprotective mechanism against 3-nitropropionic acid-induced cell death -- Paraquat: Molecular Mechanisms of Neurotoxicity and its Relation with Autophagy -- Agrochemicals-induced Dopaminergic Neurotoxicity: Role of Mitochondria-mediated oxidative stress and Protein Clearance Mechanisms -- Molecular And Neurochemical Mechanisms Dopamine Oxidation To O-Quinones In Parkinsonþs Disease Pathogenesis -- Exploring the Role of Autophagy in the Pathogenesis of Rotenone-Induced Toxicity.- Autophagic pathology and calcium deregulation in neurodegeneration
520 3 _aComprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotective mechanism. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays
710 2 _aSpringerLink (Online service)
_0Local
_9106996
942 _2lcc
_cLE
988 _aEBOOK, EBSPRINGER
650 7 _aSistema Nervioso
_xDegeneración
_9313064
_0comprobar BNE20012072191
_2embne
650 0 7 _aCiencias biomédicas
_0LocalX
_2embne
_9143729
700 1 _aFuentes, José M.
_eeditor literario
_993700
_0Local
830 0 _aCurrent Topics in Neurotoxicity
_x2363-9563
_v9
_9133172
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-13939-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901 _ai9783319139395
907 _a.b12899215
_b10-10-17
_c18-01-16
998 _am
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_a_vill
_b19-06-17
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