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007			cr nn 008mamaa
008			150102s2015 gw | s |||| 0|eng d
020			_a9783319137254
024	7		_a10.1007/978-3-319-13725-4 _2doi
040			_aES-MaUEC _bspa
050		4	_aQR186.8.E2 _bI343 2015
245	1	0	_aIgE Antibodies : _bGeneration and Function _cedited by Juan J. Lafaille, Maria A. Curotto de Lafaille.
260			_aCham, Switzerland _bSpringer _c2015
300			_a1 recurso en línea (IX, 152 páginas) _b21 ilustraciones, 16 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aCurrent Topics in Microbiology and Immunology _x0070-217X _v388
505	0		_aBiology of IgE Production: IgE Cell Differentiation and the Memory of IgE Responses -- Molecular Mechanisms of IgE Class Switch Recombination -- Anti-IgE Therapy: Clinical Utility and Mechanistic Insights -- New Insights on the Signaling and Function of the High Affinity Receptor for IgE -- Helminth-Induced IgE and Protection Against Allergic Disorders -- IgE Immunotherapy Against Cancer.
520	3		_aThis volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.
650		7	_aInmunoglobulinas _2embne _9143641
650		7	_aBiología molecular _2embne _9139103
650		0	_9139394 _aParasitología
700	1		_aLafaille, Juan J. _eeditor literario _0Local _993695
700	1		_aCurotto de Lafaille, Maria A. _eeditor literario _0Local _993696
710	2		_aSpringerLink (Online service) _0Local _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-13725-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12899173 _b10-10-17 _c18-01-16
942			_2lcc _cLE
945			_aQR186.8.E2 I343 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11568793 _z06-04-17
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0