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007			cr nn 008mamaa
008			150430s2015 gw | s |||| 0|eng d
020			_a9783319134734
024	7		_a10.1007/978-3-319-13473-4 _2doi
050		4	_aRF47.5 _b.F74 2015 EB
082	0	4	_a571.9453
245	1	0	_aFree Radicals in ENT Pathology _cedited by Josef Miller, Colleen G. Le Prell, Leonard Rybak.
264		1	_aCham _bSpringer International Publishing _bImprint: Humana Press _c2015.
300			_a1 recurso en línea (XIV, 507 páginas) _b43 ilustraciones, 32 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aOxidative Stress in Applied Basic Research and Clinical Practice _x2197-7224
505	0		_a1. Introduction -- Section 1: Basic Science of Free Radical Biology in ENT -- 2. Free radicals and oxidative stress: Basic concepts and misconceptions -- 3. A Question of Balance:Â{u01B2}ee Radicals and Cochlear Homeostasis -- 4. Antioxidants and their effect on stress-induced pathology in the inner ear -- Section 2: Epidemiology of Hearing Loss -- 5. Role of free radicals in hearing loss due to heavy metals -- 6. The role of nutrition in healthy hearing: human evidence -- Section 3: Oxidative Stress and Noise-Induced Hearing Loss -- 7. Basic mechanisms underlying noise-induced hearing loss -- 8. Oxidative stress in noise-induced hearing loss -- 9. Strategies for evaluating antioxidant efficacy in clinical trials assessing prevention of noise-induced hearing loss -- Section 4: Oxidative Stress and Drug-Induced Hearing Loss -- 10. Aminoglycoside-induced oxidative stress: pathways and protection -- 11. Hearing loss after cis-platin: oxidative stress pathways and potential for protection -- 12. Assessment of interventions to prevent drug-induced hearing loss (DIHL) -- Section 5: Oxidative Stress and Age-Related Hearing Loss -- 13. Age-related hearing loss: biochemical pathways and molecular targets -- 14. Genetics and age-related hearing loss -- 15. Mechanisms of age-related hearing loss -- 16. Interventions to prevent age-related hearing loss -- Section 6. Hereditary Hearing Loss -- 17. Genes and hearing loss: relationship to oxidative stress and free radical formation -- 18. Strategies for the treatment of hereditary hearing loss -- Section 7: Cochlear Implants, Radiation, Trauma and Other Stress Factors -- 19. Loss of Residual Hearing Initiated by Cochlear Implantation: Role of Inflammation-Initiated Cell -- 20. Role of oxidative stress in sudden hearing loss and Meniereâ€{u3824}isease -- Section 8: Head and Neck -- 21. Role of free radicals in head and neck pathology -- 22. Free radicals and sleep apnea -- 23. Free radicals in nasal and paranasal disease -- 24. Conclusion.
520			_aThis comprehensive volume examines the current state of free radical biology and its impact on otology, laryngology, and head and neck function. The chapters collectively highlight the interrelationship of basic and translational studies in each area, define the challenges to translation, and identify the existing basic issues that demand investigation as well as the opportunities for novel intervention to prevent and treat ENT pathology and impairment. In each chapter, or in some cases pairs of chapters, the author(s) have included or married issues of basic research with translational challenges and research, thus defining the pathway by which new basic insights may lead to interventions to prevent or treat impairment. The final chapter of this book reflects a meeting of all the contributors, culminating in a discussion and “white paperâ€{u0D28}at identifies the challenges to the field and defines the studies and collaborations that may lead to improved understanding of free radical biology in ENT and, subsequently,Â{u0BA5}w interventions to medically treat ENT pathology.
650		7	_a Enfermedades otorrinolaringológicas _9161938
700	1		_aLe Prell, Colleen G. _eeditor literario _0Local _1http://viaf.org/viaf/231371035 _993683
700	1		_aMiller, Josef _eeditor literario _993682 _0Local _1http://viaf.org/viaf/885194
700	1		_aRybak, Leonard _eeditor literario _993684 _0Local _1http://viaf.org/viaf/235398599
710	2		_aSpringerLink (Online service) _0Local _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-13473-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12899082 _b10-10-17 _c18-01-16
942			_2lcc _cLE
945			_aQH573-671 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11568707 _z06-04-17
988	0	0	_aEBOOK, EBSPRINGER, GOBI_sep2018
988			_aEbook_one2one
998			_aSI _a_alco _a_vill _b10/2018 _cm _dz _ef _feng _ggw _h0
999			_c81318 _d81318 _x1