000			02595nam a22003615i 4500
001			81294
003			ES-MaUEC
005			20230207040323.0
007			cr nn 008mamaa
008			141204s2015 gw | s |||| 0|eng d
020			_a9783319121369
040			_aES-MaUEC
050		4	_aRC269.5 _b.G466 2015 EB
245	0	0	_aGenomic Instability and Cancer Metastasis : _bMechanisms, Emerging Themes, and Novel Therapeutic Strategies _cedited by Chris Maxwell, Cal Roskelley
260			_aCham _bSpringer International Publishing _bSpringer _c2015
300			_a1 recurso en línea (X, 247 p.) 19 il., 18 il. col.
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aCancer Metastasis - Biology and Treatment _x1568-2102 _v20
520			_aMetastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse. This book connects cancer metastasis with genomic instability in a comprehensive manner. Section 1Â{u0BF5}tlines the fundamental mechanisms responsible for these cellular and tissue phenotypes. Section 2 discusses in silico, in vitro, and in vivo models used for the experimental study of these processes. Section 3 reviews emerging themes (ex., microenvironment, mechanotransduction, and immunomodulation), and Section 4 highlights new therapeutic approaches to overcome the unique challenges presented by the heterogeneous and metastatic tumor. This book is intended for undergraduates and postgraduates with an interest in the areas of medicine, oncology, and cancer biology as well as for the content expert searching for thorough reviews of current knowledge in these areas.
942			_2lcc _cLE
988			_aEBOOK, EBSPRINGER
650	0	4	_aMetástasis _9413460
700	1		_aMaxwell, Chris _eeditor literario _993636 _0Local
700	1		_aRoskelley, Cal _eeditor literario _993637 _0Local
830		0	_aCancer Metastasis - Biology and Treatment _x1568-2102 _v20 _9133426
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-12136-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319121369
907			_a.b12898843 _b10-10-17 _c18-01-16
998			_am _a_alco _a_vill _b10-03-17 _cm _dz _ef _feng _ggw _h0
945			_aRC269.5 .G466 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i1156846x _z06-04-17
999			_c81294 _d81294 _x1