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988			_aEbook_one2one
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003			ES-MaUEC
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007			cr nn 008mamaa
008			141128s2015 gw | s |||| 0|eng d
020			_a9783319103204
024	7		_a10.1007/978-3-319-10320-4 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH585.2 _b2015 EB
245	0	0	_aAnimal Cell Culture _cedited by Mohamed Al-Rubeai.
264		1	_aCham, Switzerland _bSpringer _c2015
300			_a1 recurso en línea (XII, 763 páginas) _b106 ilustraciones, 73 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aCell Engineering _x1389-6946 _v9
505	0		_aPreface -- 1 Cell line development -- 2 Transient recombinant protein expression in mammalian cells -- 3 Hybridoma technology for the in vitro production of therapeutic antibodies -- 4 Bioreactors for mammalian cells -- 5 Mass Transfer and Mixing Across the Scales in Animal Cell Culture -- 6 Hydrodynamic Damage to Animal Cells -- 7 Monitoring of cell culture -- 8 Serum and protein free media -- 9 Glycosylation in Cell Culture -- 10 Modelling of mammalian cell cultures -- 11 Mammalian Cell Line Selection Strategies for High-Producers -- 12 Building a Cell Culture Process with Stable Foundations: Searching for Certainty in an Uncertain World -- 13 Perfusion Processes -- 14 Single-use bioreactors for animal and human cells -- 15 An Overview of Cell Culture Engineering for the Insect Cell-Baculovirus Expression Vector System (BEVS) -- 16 Metabolic flux analysis: a powerful tool in animal cell culture -- 17 Cell immobilization for the production of viral vaccines -- 18 Cell Engineering for Therapeutic Protein Production -- 19 Proteomics in Cell Culture: From genomics to combined â€õmics for cell line engineering and bioprocess development -- 20 Metabolomics in animal cell culture -- 21 Process Analytical Technology and Quality-by-Design for Animal Cell Culture -- 22 Biosafety recommendations on the handling of animal cell cultures -- 23 Biopharmaceutical products from animal cell culture -- Index.
520			_aAnimal cells are the preferred “cell factoriesâ€{u09AF}r the production of complex molecules and antibodies for use as prophylactics, therapeutics or diagnostics. Animal cells are required for the correct post-translational processing (including glycosylation) of biopharmaceutical protein products. They are used for the production of viral vectors for gene therapy. Major targets for this therapy include cancer, HIV, arthritis, cardiovascular and CNS diseases and cystic fibrosis. Animal cells are used as in vitro substrates in pharmacological and toxicological studies. This book is designed to serve as a comprehensive review of animal cell culture, covering the current status of both research and applications. For the student or R&D scientist or new researcher the protocols are central to the performance of cell culture work, yet a broad understanding is essential for translation of laboratory findings into the industrial production. Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field to produce state-of-the-art collection of current research. A major reference volume on cell culture research and how it impacts on production of biopharmaceutical proteins worldwide, the book is essential reading for everyone working in cell culture and is aÂ{u2963}ommended volume for all biotechnology libraries.
988			_aEBOOK, EBSPRINGER, GOBI_sep2018
650		7	_aCitología _2embne _9139477
650		7	_aCélulas madre _2embne _9160528
700	1		_aAl-Rubeai, Mohamed _eeditor literario _0Local _1http://viaf.org/viaf/56765852 _986213
710	2		_aSpringerLink (Online service) _0Local _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-10320-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12898582 _b10-10-17 _c18-01-16
942			_2lcc _cLE
945			_aR-RZ EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11568203 _z06-04-17
998			_b10/2018 _dz _ek _feng _ggw _h0