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008			141122s2015 gw a s 001 0 eng d
020			_a9783319100128
024	7		_a10.1007/978-3-319-10012-8 _2doi
040			_aES-MaUEC
050		4	_aRM301 _b.I54 2015 EB
082	0	4	_a615
245	1	0	_aInflammatory Disorders _cedited by Mieczyslaw Pokorski
264		1	_aCham, Switzerland _bSpringer _c2015
300			_a1 recurso en línea (X, 67 p.) _b11 ilustraciones
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	1		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v839
505	0		_aInhaled Corticosteroids Increase Siglec-5/14 Expression in Sputum Cells of COPD Patients -- Tregs and HLA-DR Expression in Sputum Cells of COPD Patients Treated with Tiotropium and Formoterol -- Inhalation of Macrolides: A Novel Approach to Treatment of Pulmonary Infections -- Influence of Denture Plaque Biofilm on Oral Mucosal Membrane in Patients with Chronic Obstructive Pulmonary Disease -- Biophysical Activity of Animal-Derived Exogenous Surfactants Mixed with Rifampicin -- Organic Changes in the Central Nervous System in Children on Chronic Inhaled Corticosteroid Therapy -- Stem Cell Experiments Moves into Clinic: New Hope for Children with Bronchopulmonary Dysplasia -- Soluble Ligand CD40 and Uric Acid as Markers of Atheromatosis in Patients with Obstructive Sleep Apnea -- Carotid Artery Intima-Media Thickness in Hypertensive Patients with Obstructive Sleep Apnea.
520	3		_aThe mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation. The results help understand the mechanisms of action of common drugs used in COPD, such as formoterol, tiotropium, or corticosteroids, and point to novel drug targets. The chapters also deal with brain damaging effects, by far unrecognized, of inhaled corticosteroid therapy, a time-proven management of chronic inflammatory airway conditions; asthma being a case in point. Novel methods, likely less producing side effects, of macrolide antibiotics administration by inhalation are discussed, emphasizing not only bacteriostatic but also anti-inflammatory action.
650		7	_aFarmacología _0comprobar BNE19900953030 _2embne _9137893
650		7	_aBioquímica _0comprobar BNE19900962333 _2embne _9138639
650	0	7	_aInflamación _2embne _9153270
650		7	_aAparato respiratorio _xEnfermedades _0comprobar BNE19901053942 _2embne _9405936
700	1		_aPokorski, Mieczyslaw _0no2012119971 _eeditor literario _948437
830		0	_aAdvances in Experimental Medicine and Biology _x0065-2598 _v839 _9133153
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-10012-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
901			_ai9783319100128
907			_a.b12898508 _b21-10-17 _c18-01-16
942			_2lcc _cLE
945			_aRM301 .I54 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11568124 _z06-04-17
988			_aEBOOK, EBSPRINGER
998			_am _a_alco _a_vill _b21-10-17 _cm _dz _ei _feng _ggw _h0