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007			cr nn 008mamaa
008			141031s2015 gw | s |||| 0|eng d
020			_a9783319089454
024	7		_a10.1007/978-3-319-08945-4 _2doi
040			_aES-MaUEC _bspa
050		4	_aQP84.6 _bM434 2015
245	1	0	_aMechanisms of Circadian Systems in Animals and Their Clinical Relevance _cedited by Raúl Aguilar Roblero; Mauricio Díaz-Muñoz; María Luisa Fanjul de Moles
260			_aCham, Switzerland _bSpringer International Publishing _c2015
300			_a1 recurso en línea (XXIV, 380 páginas) _b83 ilustraciones, 47 ilustraciones en color
336			_aTexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_a1. Introduction to Circadian Rhythms, Clocks and its Genes -- 2. Oxidative Stress and its Role in the Synchronization of Circadian Rhythms in Crustaceans, an Ecological Perspective -- 3. Control of Rest: Activity Behavior by the Central Clock in Drosophila -- 4. Biological Rhythmicity in Subterranean Animals, a Function Risking Extinction? -- 5. Avian Circadian Organization -- 6. Functional Organization of Circadian Timing System of Diurnal Primate (Marmoset) -- 7. Intracellular Calcium as a Clock Output from Suprachiasmatic Nuclei Neurons -- 8. GABAA Receptor-Mediated Neurotransmission in the Suprachiasmatic Nucleus -- 9. Network Properties in the SCN Function -- 10. Behavioral, Physiological and Neuroendocrine Circadian Rhythms during Lactation -- 11. A Time to Wake, a Time to Sleep -- 12. Chronostasis: The Timing of Physiological Systems -- 13. Circadian rhythm and Food/Nutrition -- 14. Physiopathology of Circadian Rhythms: Understanding the Biochemical Mechanisms of Obesity and Cancer -- 15. Effects of Circadian Disruption on Physiology and Pathology: from Bench to Clinic (and Back) -- 16. Circadian Dysfunction in Huntingtonâ€{u3804}isease -- 17. Is it Possible to Modify Clock Genes to Improve Health?.
520	3		_aWell known experts in the field of Chronobiology from around the world, provide an integrative view of the state of the art of circadian biology. At present, genetic and epigenetic interaction of regulatory pathways among circadian oscillators, metabolic networks, cellular differentiation and neuronal communication are subject of intense scrutiny. The book is organized in three sections: The first includes selected examples of the circadian systems of crustaceans, insects, fish, birds and mammals. The second is a detailed view of the physiological mechanisms underlying the circadian clocks in mammals. Finally, in the third section some examples of the relevance of circadian biology and circadian misalignment to health and disease are provided including nutrition and metabolism, obesity, cancer, cardiovascular and pulmonary diseases, Huntington and affective diseases. This section concludes with a brief review on gene therapy and its potential use as a therapeutic tool to correct “clock genesâ€{u0C21}thologies. This book is aimed at all those interested in contemporary aspects of physiology, biochemistry and molecular biology applied to the study and characterization of timing systems.. It could be used as an initial approach to this field, but it also provides updated information for those already familiar with the fascinating field of Chronobiology.
650		7	_aFisiología humana _2embne _9140024
650		7	_aNeurociencias _2embne _9158907
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-08945-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12898326 _b10-10-17 _c18-01-16
942			_2lcc _cLE
945			_aQP84.6 M434 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11567946 _z06-04-17
988			_aEBOOK, EBSPRINGER, asignarmaterias_11febrero
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0