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008			151102s2015 xxu| s |||| 0|eng d
020			_a9781493932139
024	7		_a10.1007/978-1-4939-3213-9 _2doi
040			_dES-MaUEC
050		4	_aQP552.A65 _bS635 2015
245	1	0	_aSodium and Water Homeostasis : _bComparative, Evolutionary and Genetic Models _cedited by Kelly Anne Hyndman, Thomas L. Pannabecker.
260			_aNew York _bSpringer International Publishing _c2015
300			_a1 recurso en línea (VI, 325 p.) _b65 ilustraciones, 40 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aPhysiology in Health and Disease
505	0		_aIntroduction -- ANG II and water balance in frogs -- Sex differences in ANGII hypertension -- Na-K-ATPaseÂ{u2833}ubunit association with tight junction Drosophila tub size and tight junction function,- Na-K-ATPase in hypertension -- Endothelin regulation of ion transport in non-mammlian transporting epithelia -- Genetic models of Endothelin regulation of sodium transport -- miRNA and sodium and water balance in the developing zebrafish -- miRNA and sodiumand water balance in mammals -- Comparative and genetic models of WNK signaling in osmotic homeostasis -- Genetics of WNK signaling and disease in humans -- Comparative and evolutionary physiology of Water channels -- Genetic models resulting in urine concentrating defect -- Water balance in desert-adapted animals.0 Comparisons of nephron morphology and the urine concentrating mechanism -- Non-traditional models: the giraffe kidney -- Non-traditional models: insect tubule transport -- Circadian clock in ion transporters in insect vision -- Circadian clock, melatonin, and osmoregulation in fishes.Â{u282E}.
520			_aThis book presents cutting edge methods that provide insights into the pathways by which salt and water traverse cell membranes and flow in an orchestrated fashion amongst the many compartments of the body. It focuses on a number of molecular, cellular and whole animal studies that involve multiple physiological systems and shows how the internal milieu is regulated by multifactorial gene regulation, molecular signaling, and cell and organ architecture. Topics covered include: water channels, the urinary concentrating mechanism, angiotensin, the endothelin system, miRNAs and MicroRNA in osmoregulation, desert-adapted mammals, the giraffe kidney, mosquito Malpighian tubules, and circadian rhythms. The book highlights how different approaches to explaining the same physiological processes greatly increase our understanding of these fundamental processes. Greater integration of comparative, evolutionary and genetic animal models in basic science and medical science will improve our overall grasp of the mechanisms of sodium and water balance.
650		7	_2embne _9138640 _aEnzimas
700	1		_aHyndman, Kelly Anne _eeditor literario _993535 _0Local
700	1		_aPannabecker, Thomas L _eeditor literario _993536 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-3213-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12898119 _b10-10-17 _c18-01-16
942			_2lcc _cLE
945			_aQP552.A65 S635 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11567739 _z06-04-17
988			_aEBSPRINGER
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gxxu _h0