000			03420nam a22003615i 4500
999			_c81220 _d81220 _x1
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003			ES-MaUEC
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007			cr nn 008mamaa
008			150930s2015 xxu| s |||| 0|eng d
020			_a9781493930708
024	7		_a10.1007/978-1-4939-3070-8 _2doi
040			_dES-MaUEC
050		4	_aQH447 _b.G466 2015
245	1	0	_aGenomic Elements in Health, Disease and Evolution : _bJunk DNA _cedited by Kyriacos Felekkis, Konstantinos Voskarides.
250			_a1st ed. 2015.
260			_aNew York _bSpringer International Publishing _c2015
300			_a1 recurso en línea (XI, 315 p.) _b40 ilustraciones, 34 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aMicroRNAs' function and role in evolution -- MicroRNAs and disease -- piRNAs: Transposon silencing and germ line development.-Long non-coding cRNAs -- Unveiling transposable elements function to enrich knowledge for human physiology and disease pathogenesis -- Copy number variation in human health, disease and evolution -- Mini- and micro-satellite markers in health, disease and evolution -- Intron biology, focusing on group II introns, the ancestors of spliceosomal introns.-Â{u396E}ntromeres in health, disease and evolution.-Â{u3D32}ucture and functions of telomeres in organismal homeostasis and disease.-Â{u0CAF}ximal regulatory elements with emphasis on CpG rich regions.-Â{u796E}nomic analysis through high-throughput sequencing.
520			_aThis book provides a thorough review of various non-coding genomic elements and discusses in depth their role in health, disease and evolution. It begins with an exploration of non-coding RNA molecules miRNAs, piRNAs, LncRNAs and transposable elements as these moieties dominate the scientific literature the last ten years. The second part of the book discusses copy number variation regions, mini and micro satellites, and proximal and distal elements of the genome.The last section of the book focuses on the review of well-known non-coding regions of the genome, introns, centromeres and telomeres, but enriched with newly discovered functions.Â{u0073} the vast amount of data in regards to these elements is attributed to a great degree to the growing technology in the field of biomedicine, the last chapter of the book discusses the latest development in the field of Next Generation Sequence and the potential applications of this technology in the study of non-coding regions of the genome. This new volume provides an in depth background on â€j̃unk DNAâ€{u086E}d helps set the stage for future research, and is an essential tool for those in the field.
650		7	_2embne _9162605 _aGenomas
700	1		_aFelekkis, Kyriacos _eeditor literario _993533 _0Local
700	1		_aVoskarides, Konstantinos _eeditor literario _993534 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-3070-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12898107 _b10-10-17 _c18-01-16
942			_2lcc _cLE
945			_aQH447 .G466 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11567727 _z06-04-17
988			_aEBSPRINGER
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gxxu _h0