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008			150727s2015 xxu| s |||| 0|eng d
020			_a9781493928958
024	7		_a10.1007/978-1-4939-2895-8 _2doi
040			_dES-MaUEC
050		4	_aQP572.G54 _bG583 2015
245	1	0	_aGlucocorticoid Signaling : _bFrom Molecules to Mice to Man _cedited by Jen-Chywan Wang, Charles Harris.
250			_a1st ed. 2015.
260			_aNew York _bSpringer International Publishing _c2015
300			_a1 recurso en línea (XI, 385 p.) _b36 ilustraciones, 29 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v872
505	0		_aSection I: Introductory Materials -- Regulatory actions of glucocorticoid hormones: from organisms to mechanisms.-Â{u036F}lecular Biology ofÂ{u01EC}ucocorticoid Signaling.-Mechanisms of Glucocorticoid-regulated Gene Transcription -- Clinical Perspective: What do Addison and Cushing tell us about Glucocorticoid Action? -- Section II:Â{u59A6}fects of Glucocorticoids in Metabolism -- Regulation of Glucose Homeostasis by Glucocorticoids -- How do Glucocorticoids Regulate Lipid Metabolism? -- Glucocorticoids and Skeletal Muscle -- Section III:Â{u3C25}cificÂ{u59A6}fects of Glucocorticoids on Tissues -- Glucocorticoid- induced osteoporosis -- Effects of Glucocorticoids on Immune System -- Glucocorticoids and the brain: neural mechanisms regulating the stress response -- Glucocorticoid Regulation of Reproduction -- Glucocorticoids and the lung -- Glucocorticoids and the Cardiovascular System -- Glucocorticoids and Cancer -- Section IV: Miscellaneous Topics -- Animal Models of Altered Glucocorticoid Signaling -- The Dehydrogenase Hypothesis -- Conclusions and Future Directions.
520			_aThis timely volume provides a comprehensive overview of glucocorticoids and their role in regulating many aspects of physiology and their use in the treatment of disease. The book is broken into four sections that begin by giving a general introduction to glucocorticoids and a brief history of the field. The second section will discuss the effects of glucocorticoids on metabolism, while the third section will cover the effects of glucocorticoids on key tissues. The final section will discuss general topics, such as animal models in glucocorticoid research and clinical implications of glucocorticoid research. Featuring chapters from leaders in the field, this volume will be of interest to both researchers and clinicians.
650		7	_2embne _9138583 _aHormonas
700	1		_aWang, Jen-Chywan _eeditor literario _993520 _0Local
700	1		_aHarris, Charles _eeditor literario _993521 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-2895-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b1289803x _b10-10-17 _c18-01-16
942			_2lcc _cLE
945			_aQP572.G54 G583 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i1156765x _z06-04-17
988			_aEBSPRINGER
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gxxu _h0