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008			150917s2015 xxu| s |||| 0|eng d
020			_a9781493928453
024	7		_a10.1007/978-1-4939-2845-3 _2doi
040			_dES-MaUEC
050		4	_aQH603.I54 _bN684 2015
245	1	0	_aNovel Chemical Tools to Study Ion Channel Biology _cedited by Christopher Ahern, Stephan Pless.
250			_a1st ed. 2015.
260			_aNew York _bSpringer International Publishing _c2015
300			_a1 recurso en línea (VIII, 154 p.) _b33 ilustraciones, 24 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v869
520			_aThis volume describes chemical approaches to assess ion channel structure, function and pharmacology. Topics discussed include the use of engineered ionizable side chains to obtain information on permeation pathways and the local environment; the modification of engineered cysteine side chains, including cysteine scanning mutagenesis and the attachment of fluorescent probes and bio-reactive tethers; and the nascent use of genetic code expansion, evaluating its applications to ion channel and membrane proteins. This comprehensive text provides multifaceted perspectives on the great diversity of state-of-the-art methods which take advantage of the ever-expanding chemical toolbox to study ion channel biology. Capturing the contributions and innovations of renowned laboratoryÂ{u2973}earchers in transmembrane protein study for the first time, this book is comprehensive in scope. It covers a wide array of experimental approaches: photochemistry, novel biological tools, and innovative spectroscopy, all combined with traditional techniques of electrophysiology and molecular biology. Novel Chemical Tools to Study Ion Channel Biology, part of the bestselling Â{u1936}vances in Experimental Medicine and Biology series is ideal for researchers and advanced students interested in biochemistry, biophysics, fluorometry, electrophysiology, and chemical biology.
650		7	_2embne _9155847 _aCanales iónicos
700	1		_aAhern, Christopher _eeditor literario _993518 _0Local
700	1		_aPless, Stephan _eeditor literario _993519 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-2845-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12898028 _b10-10-17 _c18-01-16
942			_2lcc _cLE
945			_aQH603.I54 N684 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11567648 _z06-04-17
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