000 03315nam a22003495i 4500
999 _c81181
_d81181
_x1
001 81181
003 ES-MaUEC
005 20230207040318.0
007 cr nn 008mamaa
008 150320s2015 xxu| s |||| 0|eng d
020 _a9781493921904
024 7 _a10.1007/978-1-4939-2190-4
_2doi
040 _dES-MaUEC
050 4 _aRC553.A88
_bT446 2015
245 1 4 _aThe Molecular Basis of Autism
_cedited by S. Hossein Fatemi.
260 _aNew York
_bSpringer International Publishing
_c2015
300 _a1 recurso en línea (XVIII, 437 p.)
_b38 ilustraciones, 17 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
490 0 _aContemporary Clinical Neuroscience
505 0 _aPreface -- A Brief History of Autism -- Autism Spectrum Disorder: Diagnostic Considerations -- Epidemiologic Features of Autism Spectrum Disorders -- Genetics of Autism Spectrum Disorders: The Opportunity and Challenge in the Genetics Clinic -- Epigenetic Regulation in Autism -- Immunology of Autism -- Neuroimaging in Autism Spectrum Disorders -- The Neuropathology of Autism -- Pharmacology of ASD Spectrum Disorder -- Behavioral Therapies -- Autism and Dopamine -- Autism and Glutamate -- Serotonin in Autism Spectrum Disorder: Insights From Human Studies and Animal Models -- Oxytocin and Vasopressin in Autism and Genetic Syndromes -- Molecular basis of cholinergic changes in autistic spectrum disorders and relevance for treatment interventions -- Reelin, GABA, FMRP, and Autism -- The Role of Neurexins and Neuroligins in Autism -- Neurotrophins, their receptors and autism: ligand vs. receptor abnormalities -- Cognition, Motor Control and Other Aspects of Autism: A Pragmatic Review -- Increased vulnerability to oxidative stress and mitochondrial dysfunction in autism -- Index.
520 _aThis book is a comprehensive overview of the clinical and scientific aspects of Autism from the leading experts in the field. The clinical section covers everything from epidemiological features to epigenetic regulation to behavioral therapies and much in between. The basic science section presents the latest knowledge on the underlying causes of the disorder including the role of various neurotransmitters, neurexins and neuroligins, reelin, and other proteins. Chapters also explore the cognition and motor control in autism and the connection between oxidative stress and mitochondrial dysfunction and autism. The thorough description of these underlying causes may help researchers and clinicians find more effective treatments and therapies for the 1 in 68 American children who have been diagnosed with Autism.
650 7 _2embne
_aAutismo
_9141122
700 1 _aFatemi, S. Hossein
_eeditor literario
_980545
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-2190-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b12897711
_b10-10-17
_c18-01-16
942 _2lcc
_cLE
945 _aRC553.A88 T446 2015 EB
_g1
_ieBOOK
_j0
_lmae
_o-
_pEUR0.00
_q-
_r-
_sb
_t15
_u0
_v0
_w0
_x0
_y.i11567338
_z06-04-17
988 _aEBSPRINGER
998 _am
_a_alco
_a_vill
_b - -
_cm
_dz
_e-
_feng
_gxxu
_h4