000			04215nam a22003855i 4500
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003			ES-MaUEC
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007			cr nn 008mamaa
008			141122s2015 xxu| s |||| 0|eng d
020			_a9781493914173
024	7		_a10.1007/978-1-4939-1417-3 _2doi
040			_dES-MaUEC
050		4	_aRM281 _b.S838 2015
245	1	0	_aSubunit Vaccine Delivery _cedited by Camilla Foged, Thomas Rades, Yvonne Perrie, Sarah Hook.
260			_aNew York _bSpringer International Publishing _c2015
300			_a1 recurso en línea (XIV, 431 p.) _b65 ilustraciones, 48 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aAdvances in Delivery Science and Technology _x2192-6204
505	0		_a1 Immunological Background -- 2 Classification of Vaccines -- 3 Aluminum Adjuvants - Basic Concepts and Progress in Understanding -- 4 Emulsions as Vaccine Adjuvants -- 5 The application of liposomes as vaccine adjuvants -- 6 Developing Bilayer-based Delivery Systems for Oral Delivery of Subunit Vaccines -- 7 Cubosomes â€{u04F4}ructure, Preparation and Use as an Antigen Delivery System -- 8 ISCOMs as a Vaccine Delivery System -- 9 Virus-like Particles, a Versatile Subunit Vaccine Platform -- 10 Polymeric Particulates for Subunit Vaccine Delivery -- 11 Gels as Vaccine Delivery Systems -- 12 Implants as Sustained Release Delivery Devices for Vaccine Antigens -- 13 Dendritic Cell-based Vaccines -- 14 Parenteral Vaccine Administration â€{u0532}ied and True -- 15 Nasal Administration of Vaccines -- 16 Pulmonary Administration of Subunit Vaccines -- 17 Vaginal Delivery of Subunit Vaccines -- 18 Transcutaneous Administration -- 19 Pharmaceutical Analysis and Quality Control of Vaccines -- 20 The Physical Analysis of Vaccines -- 21 Characterizing the Association between Antigens and Adjuvants.
520			_aThis comprehensive volume compiles the concepts essential for the understanding of the pharmaceutical science and technology associated with the delivery of subunit vaccines. Twenty-one chapters are divided into four main parts: (I) Background; (2) Delivery Systems for Subunit Vaccines; (3) Delivery Routes, Devices and Dosage Forms; and (4) Pharmaceutical Analysis and Quality Control of Vaccines. Part one provide a basic background with respect to immunology and general vaccine classification. In part two, it presents representative types of vaccine delivery systems individually with focus on the physicochemical properties of the systems and their significance for the immune response they stimulate. These delivery systems include aluminum adjuvants, emulsions, liposomes, bilosomes, cubosomes/hexosomes, ISCOMs, virus-like particles, polymeric nano- and microparticles, gels, implants and cell-based delivery systems. ÂƯllowing these chapters, part three addresses the challenges associated with vaccine delivery via specific routes of administrationâ€{u9BA0}particular subcutaneous, intramuscular, oral, nasal, pulmonary, transdermal and vaginal administration. Furthermore, the specific administration routes are discussed in combination with device technologies relevant for the respective routes as well as dosage forms appropriate for the device technology. Finally, the fourth part concerns pharmaceutical analysis and quality control of subunit vaccines.
650		7	_2embne _9140409 _aVacunas
700	1		_aFoged, Camilla _eeditor literario _993440 _0Local
700	1		_aRades, Thomas _eeditor literario _993441 _0Local
700	1		_aPerrie, Yvonne _eeditor literario _984610 _0Local
700	1		_aHook, Sarah _eeditor literario _993442 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4939-1417-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12897589 _b10-10-17 _c18-01-16
942			_2lcc _cLE
945			_aRM281 .S838 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i1156720x _z06-04-17
988			_aEBSPRINGER
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gxxu _h0