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008			141021s2015 xxk| s |||| 0|eng d
020			_a9781447165392
024	7		_a10.1007/978-1-4471-6539-2 _2doi
040			_dES-MaUEC
050		4	_aQR171 _b.M483 2015
245	1	0	_aMetabonomics and Gut Microbiota in Nutrition and Disease _cedited by Sunil Kochhar, FranÃ{u00A7}ois-Pierre Martin.
260			_aLondon _bSpringer International Publishing _c2015
300			_a1 recurso en línea (XVI, 375 p.) _b54 ilustraciones, 43 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aMolecular and Integrative Toxicology _x2168-4219
505	0		_aIntroduction to Metabolomics in systems biology research -- Metabolomics in clinical practice.-Adopting multivariate non-parametric tools to determine genotype-phenotype interactions in health and disease -- Metabolomics in Translational Research for Personalized Medicine and Nutrition -- Can we use Metabolomics to Understand Changes to Gut Microbiota Populations and Function? A Nutritional Perspective -- Automated annotation of microbial and human flavonoid derived metabolites -- Metabonomics in neonatal and paediatric research: Studying and modulating gut functional ecology for optimal growth and development -- Metabolomics and Milk: the Development of the Microbiota in Breast Fed Infants -- Metabonomics and gut microbial paradigm in healthy ageing -- Roles of herbal medicine in modulating gut microbiota associated with health and diseases -- Gut microbiota and metabolic diseases: from pathogenesis to therapeutic perspective -- Role of microbiota in regulating host lipid metabolism and disease risk -- Role of the Gut Microbiota in Maintaining GI Health: Highlights on Inflammatory Bowel Disease -- Deciphering the gut microbial contribution to the aetiology of autism development -- The Modulation of Drug Efficacy and Toxicity by the Gut Microbiome -- Understanding the benefits of bariatric surgery on gut physiology: implications for obesity, type 2 diabetes and cardiovascular disease.
520			_aThis book provides a comprehensive overview of metabonomics and gut microbiota research from molecular analysis to population-based global health considerations. The topics include the discussion of the applications in relation to metabonomics and gut microbiota in nutritional research, in health and disease and a review of future therapeutical, nutraceutical and clinical applications. It also examines the translatability of systems biology approaches into applied clinical research and to patient health and nutrition. The rise in multifactorial disorders, the lack of understanding of the molecular processes at play and the needs for disease prediction in asymptomatic conditions are some of the many questions that system biology approaches are well suited to address. Achieving this goal lies in our ability to model and understand the complex web of interactions between genetics, metabolism, environmental factors, and gut microbiota. Being the most densely populated microbial ecosystem on earth, gut microbiota co-evolved as a key component of human biology, essentially extending the physiological definition of humans. Major advances in microbiome research have shown that the contribution of the intestinal microbiota to the overall health status of the host has been so far underestimated. Human host gut microbial interaction is one of the most significant human health considerations of the present day with relevance for both prevention of disease via microbiota-oriented environmental protection as well as strategies for new therapeutic approaches using microbiota as targets and/or biomarkers. In many aspects, humans are not a complete and fully healthy organism without their appropriate microbiological components. Increasingly, scientific evidence identifies gut microbiota as a key biological interface between human genetics and environmental conditions encompassing nutrition. Microbiota dysbiosis or variation in metabolic activity has been associated with metabolic deregulation (e.g. obesity, inflammatory bowel disease), disease risk factor (e.g. coronary heart disease) and even the aetiology of various pathologies (e.g. autism, cancer), although causal role into impaired metabolism still needs to be established. Metabonomics and Gut Microbiota in Nutrition and Disease serves as a handbook for postgraduate students, researchers in life sciences or health sciences, scientists in academic and industrial environments working in application areas as diverse as health, disease, nutrition, microbial research and human clinical medicine. Â{uE000}
650		7	_2embne _9138717 _aMicroorganismos
700	1		_aKochhar, Sunil _eeditor literario _993404 _0Local
700	1		_aMartin, FranÃ{u00A7}ois-Pierre _eeditor literario _993405 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4471-6539-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12897413 _b10-10-17 _c18-01-16
942			_2lcc _cLE
945			_aQR171 .M483 2015 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i1156703x _z06-04-17
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