000			04022nam a22003615i 4500
999			_c80646 _d80646 _x1
001			80646
003			ES-MaUEC
005			20230202102722.0
007			cr nn 008mamaa
008			140723s2014 ja | s |||| 0|eng d
020			_a9784431549659
024	7		_a10.1007/978-4-431-54965-9 _2doi
040			_dES-MaUEC
050		4	_aRE551 _b.N487 2014
245	1	0	_aNeuroprotection and Neuroregeneration for Retinal Diseases _cedited by Toru Nakazawa, Yasushi Kitaoka, Takayuki Harada.
260			_aTokyo _bSpringer International Publishing _c2014
300			_a1 recurso en línea (X, 356 p.) _b85 ilustraciones, 61 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aPart I Neuroprotection for Glaucoma -- 1. Molecular Architecture of Glutamate Signaling Pathway in Glaucomatous Optic Neuropathy -- 2. Calcium and Calpain Activation -- 3. Classical Signaling Pathways -- 4. Antioxidative Treatment for Neuroprotection in Glaucoma -- 5. ER stress -- 6. Nitric Oxide Contributes to Retinal Ganglion Cell Survival Through Protein S-Nitrosylation after Optic Nerve Injury -- 7. Neurotrophic factors -- 8. RIP Kinase-Mediated Programmed Necrosis -- 9. Axonal Degeneration -- 10. Axonal Transport -- 11. Interaction Between RGC Bodies and Glia -- 12. Aquaporin in optic neuropathies -- 13. Microglia -- Part II Neuroprotection for Age-Related Macular Degeneration (AMD), Retinal Pigmentary Degeneration -- 14. Neuroprotection for Photoreceptors -- 15. Retinal Photooxidative Stress and Its Modifiers -- 16. Roles of the Retinal Pigment Epithelium in Neuroprotection -- 17. Oxidative Stress in the RPE and Its Contribution to AMD Pathogenesis; Implication of Light Exposure -- 18. Interaction Between Photoreceptors and RPEs -- Part III Neuroprotection for Other Retinal Diseases -- 19. Neuroprotection for Retinal Detachment -- 20. Neuroinflammation -- 21. Optic Neuritis -- 22. Neuroprotection by Endothelial Progenitor Cells for Retinal Degeneration -- 23. Optic Nerve Regeneration.
520			_aThis book provides the latest findings on neuroprotection and neuroregeneration as potential therapeutic strategies for various eye diseases, namely, glaucoma, age-related macular degeneration (AMD), retinal detachment, and retinitis pigmentosa. Glaucoma is one of the main causes of blindness throughout the world, and other diseases such as AMD and retinitis pigmentosa also lead to loss of vision. All these conditions are characterized by degeneration of specific retinal cell types, making it essential to establish treatments to protect retinal neurons and the optic nerve. With that aim in mind, this book explains the mechanisms underlying aforementioned diseases and their experimental models. The novel strategy proposals for the treatment of retinal diseases based on the concept of neuroprotection are also discussed in the main body of the text, while the section on regenerative research discusses optic nerve regeneration, endothelial progenitor cells, and iPS cells. This book is recommended as a professional reference work for all doctors and trainees in the field of ophthalmology who are interested in neuroprotective and neuroregenerative treatments.
650		7	_2embne _9190667 _aRetina _xEnfermedades
700	1		_aNakazawa, Toru _eeditor literario _989014 _0Local
700	1		_aKitaoka, Yasushi _eeditor literario _989015 _0Local
700	1		_aHarada, Takayuki _eeditor literario _989016 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-4-431-54965-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12883992 _b10-10-17 _c11-11-15
942			_2lcc _cLE
945			_aRE551 .N487 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11563813 _z06-04-17
988			_aEBSPRINGER
998			_am _a_alco _a_vill _b11-11-15 _cm _dz _e- _feng _gja _h0