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020 _a9784431547891
024 7 _a10.1007/978-4-431-54789-1
_2doi
050 4 _aRC845
_b.A986 2014
245 1 0 _aAutoimmune Liver Diseases :
_bPerspectives from Japan
_cedited by Hiromasa Ohira.
260 _aTokyo
_bSpringer
_c2014
300 _a1 recurso en línea (VIII, 305 páginas)
_b70 ilustraciones, 44 ilustraciones en color
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _aPreface -- Part IÂ{u1D74}toimmune Hepatitis.-Â{u0C42}{u0874}hogenesis of Autoimmune Hepatitis-. 2Â{u1BA9}imal Models of Autoimmune Hepatitis -- 3Â{u5C29}idemiology and Natural History in Japan -- 4Â{u8A73}stological Findings of Autoimmune Hepatitis -- 5Â{u4A61}agnosis of Autoimmune Hepatitis -- 6Â{u18F5}ute Presentation of Autoimmune Hepatitis -- 7Â{u4CA5}atment of Autoimmune Hepatitis -- 8Â{uD86E}nagement Strategies for Autoimmune Hepatitis Treatment Non-Responders -- 9Â{u0964}iatric Autoimmune Hepatitis -- 10Â{uEBEE}nalcoholic Steatohepatitis -Autoimmune Hepatitis Overlap -- 11Â{u99C7}G4-Related Autoimmune Hepatitis -- Part II Primary Biliary Cirrhosis -- 12Â{u4A25} Onset Mechanism of Primary Biliary Cirrhosis -- 13Â{u796E}netic Factors in Pathogenesis of Primary Biliary Cirrhosis -- 14Â{u1BA9}imal Models of Primary Biliary Cirrhosis -- 15Â{u5C29}idemiology and Natural History in Japan -- 16Â{uE977}w Histological Staging and Grading System for Primary Biliary Cirrhosis -- 17Â{u1D74}toantibodies in Primary Biliary Cirrhosis -- 18Â{u4A61}agnosis and UDCA Treatment of Primary Biliary Cirrhosis -- 19Â{u297A}zafibrate Treatment of Primary Biliary Cirrhosis -- 20Â{uD86E}nagement the Patients with Feature of Autoimmune Hepatitis -- 21Â{uCA76}ver Transplantation for Primary Biliary CirrhosisÂ{u282E}.
520 3 _aAutoimmune Liver Diseases summarizes the recent high-impact research and clinical findings obtained in Japan in the study and treatment of autoimmune liver diseases. Although these disorders are relatively rare, they are recognized as an important group of refractory liver diseases, the most common of which are autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC). The book therefore comprises two major sections, one dealing with AIH, the other with PBC. AIH in Japanese patients creates a unique disease population, as its clinical features are different from those of Western patients resulting from the different genetic background of the two patient populations. Also, mouse models of neonatal thymectomy-PD-1 knockout mice, clinical analyses of acute hepatitis-like manifestations, and research findings on IgG4-related autoimmune hepatitis have been reported in Japan and are included in this book. A disease-susceptibility gene specific to Japanese PBC patients has also recently been discovered. Because of the relatively homogeneous population of Japan, analyses conducted with Japanese PBC patients have yielded findings that are highly relevant to the pathogenesis of the disease. Furthermore, new pathological staging criteria, anti-gp210 antibodies and the basis they provide for improved accuracy of prognosis, treatment with bezafibrate, and the outcomes of living-donor liver transplantation are also presented here. This volume therefore serves as a useful resource not only for hepatologists, but also for researchers, clinical residents, and medical students both in Japan and in other countries.
710 2 _aSpringerLink (Online service)
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988 _aEBOOK, asignarmaterias, EBSPRINGER,
650 7 _aMedicina clínica
_2embne
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650 2 7 _aHepatología
_2embne
_9143270
700 1 _aOhira, Hiromasa
_eeditor literario
_989011
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-4-431-54789-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
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