000 02700nam a22003615i 4500
001 80617
003 ES-MaUEC
005 20230207040313.0
007 cr nn 008mamaa
008 130913s2014 au | s |||| 0|eng d
020 _a9783709106877
024 7 _a10.1007/978-3-7091-0687-7
_2doi
050 4 _aRC394.D35
_bM858 2014
245 1 0 _aMultiple System Atrophy
_cedited by Gregor K. Wenning, Alessandra Fanciulli.
260 _aVienna
_bSpringer
_c2014
300 _a1 recurso en línea (XVI, 198 páginas)
_b33 ilustraciones, 20 ilustraciones en color
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _a1. Historical Review -- 2. Epidemiology -- 3. Neuropathology -- 4. Etiopathogenesis -- 5. Animal Models -- 6. Clinical Presentation -- 7. Clinical diagnostic Criteria -- 8. Natural History -- 9. Investigations -- 10. Tratment.
520 3 _aThis textbook provides a comprehensive monography on multiple system atrophy (MSA), a rare and fatal neurodegenerative disorder that presents with autonomic failure and either parkinsonism (MSA-P) or cerebellar ataxia (MSA-C).The underlying neuropathology of MSA is characterized by striatonigral degeneration (SND), olivopontocerebellar atrophy (OPCA) and unique oligodendroglial cytoplasmic alpha-synuclein inclusions. MSA is therefore classified among the alpha-synucleinopathies such as Parkinson`s disease, pure autonomic failure and dementia with Lewy bodies. Over the last decade there have been important advances in early diagnosis, pathogenesis research and clinical trial activity. The monography will cover the entire spectrum ranging from molecular and genetic work to symptomatic and interventional therapies. The book is written for movement disorder clinicians and basic neuroscientists interested in degenerative movement disorders.
710 2 _aSpringerLink (Online service)
_0Local
_9106996
942 _2lcc
_cLE
988 _aEBOOK, asignarmaterias, EBSPRINGER,
650 7 _aNeurociencias
_0
_2embne
_9158907
650 2 7 _aNeurociencias
_0
_2embne
_9158907
700 1 _aWenning, Gregor K
_eeditor literario
_988948
_0Local
700 1 _aFanciulli, Alessandra
_eeditor literario
_988949
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-7091-0687-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b12883700
_b10-10-17
_c11-11-15
998 _am
_a_alco
_a_vill
_b11-11-15
_cm
_dz
_e-
_feng
_gau
_h0
945 _aRC394.D35 M858 2014 EB
_g1
_ieBOOK
_j0
_lmae
_o-
_pEUR0.00
_q-
_r-
_sb
_t15
_u0
_v0
_w0
_x0
_y.i11563527
_z06-04-17
999 _c80617
_d80617
_x1