000			04046nam a22003495i 4500
999			_c80512 _d80512 _x1
001			80512
003			ES-MaUEC
005			20230202102627.0
007			cr nn 008mamaa
008			131129s2014 gw | s |||| 0|eng d
020			_a9783642394959
024	7		_a10.1007/978-3-642-39495-9 _2doi
040			_dES-MaUEC
050		4	_aRC952 _b.I468 2014
245	1	0	_aImmunology of Aging _cedited by Ahmad Massoud, Nima Rezaei.
260			_aBerlin, Heidelberg _bSpringer International Publishing _c2014
300			_a1 recurso en línea (XIX, 406 p.) _b31 ilustraciones, 29 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aAn Introduction on the old age and aging of the immune system -- The immune system, a marker and modulator of the rate of aging -- Age-associated alterations of pleiotropic stem cell and the therapeutic implication of stem cell therapy in aging -- A role for epigenetic modulation of the innate immune response during aging -- Basophil, eosinophil and neutrophil functions in the elderly -- Dendritic cells and dysregulated immunity in the elderly -- Natural killer cell immunosenescence and cancer in the elderly -- Pattern recognition receptors and aging -- Impact of ageing on T cell repertoire and immunity -- T cell mediated immunity in the immunosenescence process -- Biological and phenotypic alterations of T cells in aging -- T cells seen from the metabolic and aging perspective -- Age-related alterations in regulatory T cells -- Effects of aging on B cells -- The role of MicroRNAs in immunosenescence process -- Immunogenetics of Aging -- Aging immunity and infection -- Influenza infection in the elderly -- Optimising response to vaccination in the elderly -- Nutrition, immunity and aging -- Diet and immunosenescence -- Dietary Intake and impact of zinc supplementation on the immune functions in elderly: nutrigenomic approach -- Physiological and pathological role of reactive oxygen species in the immune cells -- Oxidative stress in aging -- Skin aging and the immune system -- Aging immunity and the impact of physical exercise.
520			_aThe rapidity of scientific progress over the last few years guarantees the utility of a new collection of state-of-the-art reviews on the immunology of ageing. The aim of this authoritative book is to summarize current knowledge on the cellular and molecular aspects of the ageing immune system and their clinical relevance. The book is a result of extensive collaboration of more than sixty of the greatest thinkers and scholars in the field, in cooperation with a number of junior colleagues. Â{u026D}munology of Aging presents the most up-to-date information on the scientific issues addressed by research into ageing of the immune system, providing insights into the effects of this process on susceptibilities to those diseases which are most common among elders. The retrieval strategies used to slow down the decline in the immune system in the elderly are another subject detailed extensively. ¹ providing a broad overview of immunosenescence and its consequences, as well as their potential modulation, this book will fill a gap in a timely manner. It will be of value to all immunologists, whether novice or experienced, as well as geriatricians and epidemiologists.
650		7	_2embne _9140743 _aGeriatría
700	1		_aMassoud, Ahmad _eeditor literario _988760 _0Local
700	1		_aRezaei, Nima _eeditor literario _988761 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-642-39495-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12882653 _b10-10-17 _c11-11-15
942			_2lcc _cLE
945			_aRC952 .I468 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i1156247x _z06-04-17
988			_aEBSPRINGER
998			_am _a_alco _a_vill _b11-11-15 _cm _dz _e- _feng _ggw _h0