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020 _a9781447165033
024 7 _a10.1007/978-1-4471-6503-3
_2doi
040 _dES-MaUEC
050 4 _aRC382
_b.L486 2014
245 1 0 _aLevodopa-Induced Dyskinesia in Parkinson's Disease
_cedited by Susan H. Fox, Jonathan M. Brotchie.
260 _aLondon
_bSpringer International Publishing
_c2014
300 _a1 recurso en línea (XII, 368 p.)
_b12 ilustraciones, 11 ilustraciones en color
336 _aTexto (visual)
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _aPhenomenology of Levodopa-Induced Dyskinesia -- Dyskinesia Rating Scales in Parkinson's Disease -- Epidemiology of Levodopa-Induced Dyskinesia -- Risk Factors for Levodopa-Induced Dyskinesia -- Pharmacological Treatment Options for Levodopa-Induced Dyskinesia -- Surgical Options for Levodopa-Induced Dyskinesia in Parkinsonâ€{u3804}isease -- Basal Ganglia Circuitry Models of L-DOPA-Induced Dyskinesia -- Basal Ganglia Circuitry Models of L-DOPA-Induced Dyskinesia -- Pharmacological Properties of Levodopa -- Dopamine Receptors and LID -- The Serotonergic System In Levodopa-Induced Dyskinesia -- The Opioid System in Levodopa-Induced Dyskinesia -- Glutamate Receptors and Levodopa-Induced Dyskinesia -- Cannabinoids and Levodopa-Induced Dyskinesia -- The Role of the Noradrenergic System and its Receptors In Levodopa-Induced Dyskinesia -- Involvement of the Cholinergic System in Levodopa-Induced Dyskinesia -- New Clinical Trials for Levodopa-Induced Dyskinesia -- Preclinical Models of Levodopa-Induced Dyskinesia -- Final Thoughts: Summary and Future Therapeutic Strategies in LID.
520 _aThis book aims to provide a single reference source on levodopa-induced dyskinesias (LID) from â€b̃ench to bedsideâ€{uE809}nitial chapters review the clinical features and phenomenology of LID with video examples; epidemiology and genetic risk factors for LID are covered as a background to understanding risk factors for developing LID. The following chapters cover the latest preclinical studies aiming to understand the pathophysiology of LID at the cellular, neurochemical, neurophysiological and circuitry level with detailed discussion of mechanisms and future directions to take the field forward; clinical studies from phase II to phase IV; ongoing RCTs in LID; and evidence-based medicine reviews of treatment options.Âv̥odopa-Induced Dyskinesia in Parkinsonâ€{u3804}isease is aimed at an international audience of movement disorder neurologists; neuroscientists; trainees; and graduate and post-graduate students.
650 7 _2embne
_aSistema nervioso central
_xEnfermedades
_9188115
650 7 _2embne
_9141804
_aParkinson, Enfermedad de
700 1 _aFox, Susan H.
_eeditor literario
_0Local
_988026
700 1 _aBrotchie, Jonathan M.
_eeditor literario
_0Local
_988027
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4471-6503-3
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907 _a.b12878728
_b10-10-17
_c11-11-15
942 _2lcc
_cLE
945 _aRC382 .L486 2014 EB
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