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020 _a9781447163503
024 7 _a10.1007/978-1-4471-6350-3
_2doi
050 4 _aRC685.V2
_bM654 2014
245 1 0 _aMolecular Biology of Valvular Heart Disease
_cedited by Nalini M. Rajamannan.
260 _aLondon
_bSpringer
_c2014
300 _a1 recurso en línea (XVII, 150 páginas)
_b60 ilustraciones, 50 ilustraciones en color
336 _aTexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
505 0 _aCalcific Aortic Valve Disease: The Role of the Stem Cell Niche -- In vitro Cell Culture Model of Calcification: Molecular Regulation of Myofibroblast Differentiation to an Osteoblast Phenotype -- Aortic Valve Apoptosis, Cell Proliferation and Atherosclerosis in Experimental Hypercholesterolemia -- Experimental Model of Aortic Valve Calcification to Induce Osteoblast Differentiation -- Development of an Experimental Model of Mitral Valve Regurgitation via Hypertrophic Chondrocytes -- Testing Drug Eluting Paclitaxel Balloon Valvuloplasty in an Experimental Model of Aortic Stenosis -- Ex vivo model for Bioprosthetic Valve Calcification via Stem Cell Differentiation -- Experimental Hypercholesterolemia in Genetic ApoE-/-/Lrp5-/- Mice: Proof of Principle -- Wnt3a-Lrp5 mediated Bicuspid Aortic Valve Disease -- Mouse Models of Calcific Aortic Valve Disease -- Hemodynamic Mechanisms of Bicuspid Aortic Valve Calcification and Aortopathy -- Bioreactor and biomaterial platforms for investigation of mitral valve biomechanics and mechanobiology -- Identification of early pathological events in calcific aortic valve disease by molecular imaging -- Role of ectonucleotidases and purinergic receptors in calcific aortic valve disease -- In vitro model of Drug Testing -- Application of the LDL-Density-Pressure Theory: The Mitral Valve -- Application of The LDL-Density-Radius Theory: The Aortic Valve.
520 3 _aThis book presents the cellular details and the basic molecular biology approaches for understanding cardiac valvular disease. It provides novel cellular targets for developing future clinical trials and comprehensive clinical discussion of this expanding field. Molecular Biology of Valvular HeartÂ{u4A73}sease will guide physicians on the potential medical therapies to treat valvular heart disease while providing a platform for cellular targeting of valvular heart disease. Residents and fellows in cardiology, interventional cardiology, cardiac surgery, and current and future valve biologists alike will find this book to be an invaluable resource for developing further interest and understanding of the cellular basis for cardiac valvular disease treatment.
710 2 _aSpringerLink (Online service)
_0Local
_9106996
942 _2lcc
_cLE
988 _aEBOOK, asignarmaterias, EBSPRINGER,
650 7 _9138557
_aCardiología
_2embne
650 7 _9138557
_aCardiología
_2fast
700 1 _aRajamannan, Nalini M
_eeditor literario
_988012
_0Local
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-1-4471-6350-3
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
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