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003			ES-MaUEC
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007			cr nn 008mamaa
008			141016s2014 ja | s |||| 0|eng d
020			_a9784431551393
024	7		_a10.1007/978-4-431-55139-3 _2doi
040			_dES-MaUEC
050		4	_aR857.T55 _bA337 2014
100	1		_aAkashi, Misturu _eeditor literario _0Local _986907
245	1	0	_aEngineered Cell Manipulation for Biomedical Application _cedited by Misturu Akashi, Takami Akagi, Michiya Matsusaki.
260			_aTokyo _bSpringer International Publishing _c2014
300			_a1 recurso en línea (VIII, 271 p.) _b93 ilustraciones, 79 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
490	0		_aNanomedicine and Nanotoxicology _x2194-0452
505	0		_aRecent Advances in 3D Tissue Models -- Rapid Assembly of Cellular Aggregation Using Micro-Nano Technologies -- Rapid Single Cells Printing by Piezoelectric Inkjet Printer -- Engineering Electrospun Scaffolds to Encourage Cell Infiltration -- The Potential Use of Three-Dimensional Cellular Multilayers as a Blood Vessel Model -- Engineering Cellular Assembly for Applications in Regenerative Medicine -- Hepatic Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells by Two- and Three-Dimensional Culture Systems in vitro -- Reconstruction of Elastic Fibers in Three-Dimensional Smooth Muscle Cells -- Building Experimental System Modeling Fibrotic Tissue in Human Pancreatic Cancer by Three-Dimensional Layer-by-Layer Culture -- Human Living Skin Equivalents as a Promising Model for Skin Grafts -- Particulate and Immunity -- Functional Nanoparticles for Vaccine Delivery Systems -- Nanoparticle-Based Specific Targeting of Antigen-Presenting Cells for Immunotherapy -- Barrier Signalling -- The Absorption, Distribution, Metabolism, and Excretion Profile of Nanoparticles.
520			_aThis book is the first to summarize new technologies for engineered cell manipulation. The contents focus on control of cellular functions by nanomaterials and control of three-dimensional cellâ€{u396C}l interactions. Control of cellular functions is important for cell differentiation, maturation, and activation, which generally are controlled by the addition of soluble cytokines or growth factors into cell culture dishes. Target antigen molecules can be efficiently delivered to the cytosol of the dendritic cells using the nanoparticle technique described here, and cellular functions such as dendritic cell maturation can be controlled easily and with precision. This book describes basic preparation of the nanoparticles, activation control of dendritic cells, immune function control, and in vivo application for various vaccination systems. The second type of control, that of cellâ€{u396C}l interaction, is important for tissue engineering in order to develop three-dimensional cellular constructs. To achieve in vitro engineering of three-dimensional human tissue constructs, cellâ€{u396C}l interaction must be controlled in three dimensions, but typical biological cell manipulation technique cannot accomplish this task. An engineered cell manipulation technique is necessary. In this book the authors describe the fabrication of nanofilms onto cell surfaces, development of three-dimensional cellular multilayers, and various applications of the cellular multilayers as three-dimensional human models. This important work will be highly informative for researchers and students in the fields of materials science, polymer science, biomaterials, medicinal science, nanotechnology, biotechnology, and biology.
650		7	_2embne _aTejidos (Biología) _9668849
700	1		_aAkagi, Takami _eeditor literario _986908 _0Local
700	1		_aMatsusaki, Michiya _eeditor literario _986909 _0Local
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-4-431-55139-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12843854 _b10-10-17 _c23-02-15
942			_2lcc _cLE
945			_aR857.T55 A337 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11556766 _z06-04-17
988			_aEBSPRINGER
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _gja _h0