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001			77903
003			ES-MaUEC
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007			cr nn 008mamaa
008			141114s2014 au | s |||| 0|eng d
020			_a9783709114315
024	7		_a10.1007/978-3-7091-1431-5 _2doi
040			_aES-MaUEC
050		4	_aRC280.B7 _bG574 2014 EB
082	0	4	_a612.8
700	1		_aSedo, Aleksi. _eeditor literario. _986897 _0Local _0http://id.loc.gov/authorities/names/n2015181699 _1http://viaf.org/viaf/314899199
245	0	0	_aGlioma Cell Biology _cedited by Aleksi Sedo, Rolf Mentlein.
264		1	_aVienna _bSpringer _c2014
300			_a1 recurso en línea (X, 468 páginas) _b56 ilustraciones, 52 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aThe inner space: Molecular mechanisms driving the malignant phenotype of glioma cells: Cancer stem cells and glioblastoma -- Epigenetic changes in gliomas -- Signaling cascades and transcription factors driving the malignant phenotype of glioma cells -- MicroRNAs in molecular pathology of gliomas -- Autophagy in glioma cells.-Â{u2820} Partnership: Glioma cell partners and the tumor microenvironment: Auto- and paracrine mediators in the glioma microenvironment -- Angiogenesis in gliomas -- Immune response â€{u09EC}iomas-associated immunosuppression -- Microglia in gliomas: friend or foe? Glioma and Extracellular Matrix -- Glioblastomas and the special role of adhesion molecules in their invasion -- Glioma-associated proteases -- Interactions: Concepts and tools in glioma research:- Experimental models of glioma -- Models to study glioma cell invasion. Â{u2802}Â{u2802}Â{u2802}Â{u2802}Â{uE000}
520			_aGliomas are fatal diseases, but also represent good models for tumorÂ{u2973}earch with the aim to eventually discover new and appropriate therapeutics against this disease. Glioma experimental research models are of help to investigate tumorigenesis (tumor stem cell theory versus "classical" opinions),Â{u0D35}mor angiogenesis (since they are highly vascularized) and tumor invasion (since they grow without limits). In addition, they have a very special microenvironment (the brain) and limited tumor stroma cells (mainly microglia and endothelial cells). This book addresses the molecular mechanisms of the various tumor stages, describes the interaction with the tumor microenvironment and furthermore depicts experimental models for Glioma research and future therapeutic concepts. The book is composed and written for Scientists and Medical Doctors in Oncology, Neurosciences and Molecular Biology
650		7	_aCerebro _xTumores _9214753
650		7	_aCáncer _xInvestigación _2embne _9182523
700	1		_aMentlein, Rolf _eeditor literario _986898 _0Local _0http://id.loc.gov/authorities/names/n96098820 _1http://viaf.org/viaf/165537122
710	2		_aSpringerLink (Online service) _0Local _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-7091-1431-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12843829 _b10-10-17 _c23-02-15
942			_2lcc _cLE
945			_aRC321-580 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11556730 _z06-04-17
988	0	0	_aEBOOK, EBSPRINGER, GOBI_sep2018
988			_aEbook_one2one
998			_aSI _a_alco _a_vill _b10/2018 _cm _dz _ef _feng _gau _h0
999			_c77903 _d77903 _x1