000			03171nam a22003375i 4500
999			_c77875 _d77875 _x1
001			77875
003			ES-MaUEC
005			20230202102341.0
007			cr nn 008mamaa
008			141006s2014 gw | s |||| 0|eng d
020			_a9783319094984
024	7		_a10.1007/978-3-319-09498-4 _2doi
040			_dES-MaUEC
050		4	_aQR187.5 _bP375 2014
100	1		_aParker, Dane. _eeditor literario _986855 _0Local
245	1	0	_aBacterial Activation of Type I Interferons _cedited by Dane Parker.
260			_aCham, Switzerland _bSpringer International Publishing _c2014
300			_a1 recurso en línea (VII, 129 p.) _b12 ilustraciones, 10 ilustraciones en color
336			_aTexto (visual) _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
505	0		_aProduction and action of type I interferons in host defense -- Induction and consequences of the type I IFN response to Listeria monocytogenes -- Innate immune and type I IFN responses during Legionella pneumophila infection -- Type I interferons in immune defense against streptococci -- Activation of type I IFN signaling by Staphylococcus aureus -- Contribution of interferon signaling to host defense against Pseudomonas aeruginosa -- The detrimental role of type I interferon signaling during infection with Salmonella typhimurium -- Yersinia activation of type I interferon -- Induction and Function of Type I IFNs During Chlamydial Infection -- Regulation of Host Response to Mycobacteria by Type I Interferons.
520			_aThe type I interferon (IFN) signaling pathway is well recognized as a pathway activated by viral infections. It is activated by a variety of microbial pattern recognition receptors including the Toll-like receptors, NOD-like receptors and several cytosolic receptors. Activation of the type I IFN pathway leads to the production of both antiviral factors and products that influence immune cell function. More recently it has been shown that bacteria are also capable of activating this pathway. Bacterial Activation of Type I Interferons reviews both the current understanding of how different bacterial species are able to activate this pathway as well as the influence type I IFNs have on the outcome to infection. Several different bacterial species are covered, spanning Gram positive and Gram negative, intracellular, extracellular, and different host infection sites. An introduction to the pathogenesis of each organism is provided, and the signaling molecules involved in the activation of the type I IFN pathway and the role it plays in animal infection models are also covered.
650		7	_2embne _aInmunología _9138330
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/978-3-319-09498-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
907			_a.b12843544 _b10-10-17 _c23-02-15
942			_2lcc _cLE
945			_aQR187.5 P375 2014 EB _g1 _ieBOOK _j0 _lmae _o- _pEUR0.00 _q- _r- _sb _t15 _u0 _v0 _w0 _x0 _y.i11556456 _z06-04-17
988			_aEBSPRINGER
998			_am _a_alco _a_vill _b - - _cm _dz _e- _feng _ggw _h0